Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YWHAH
  • Mouse genes Ywhah
  • Rat genes Ywhah
  • Zfish genes ywhah
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ywhah

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Ywhah	IDA		Mouse	MGI:MGI:3693396|PMID:12176032
Molecular Function	GO:0019899	enzyme binding	YWHAH	IPI	UniProtKB:Q13370	Human	PMID:17255105
Molecular Function	GO:0042802	identical protein binding	YWHAH	IPI	UniProtKB:Q04917	Human	PMID:17085597
Molecular Function	GO:0042802	identical protein binding	YWHAH	IPI	UniProtKB:Q04917	Human	PMID:17979178
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	YWHAH	IPI	UniProtKB:P04150	Human	PMID:9079630
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P30305	Human	PMID:10713667
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P22681	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96B36	Human	PMID:12524439
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P27448	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P41743	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8TEW0	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96L34	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9BYG4	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9BYG5	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9NPB6	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99759	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99683	Human	PMID:15023544
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:O60565	Human	PMID:16545136
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P30305	Human	PMID:16672277
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:O94921	Human	PMID:16775625
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P27448	Human	PMID:16959763
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:16959763
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96L34	Human	PMID:16959763
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99683	Human	PMID:17700517
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9BZL6	Human	PMID:17962809
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P27448	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P41743	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P56524	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8TEW0	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q92934	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96B36	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P56524	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8N5S9	Human	PMID:18242179
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q6VV64	Human	PMID:18397886
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q14678-2	Human	PMID:18458160
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9UQC2	Human	PMID:19172738
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:19553522
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96PX8	Human	PMID:19640509
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P67828	Human	PMID:19860830
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q5S007	Human	PMID:20642453
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P62258	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q92934	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q5S007	Human	PMID:23075850
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8WUA7	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9NU19	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9UBF8	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P61588	Human	PMID:23622247
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P56524	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P37840	Human	PMID:24895406
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P37840-1	Human	PMID:24895406
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P22681	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P30305	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P56524	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P62258	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9BYG5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:O15553	Human	PMID:27030597
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:O94921	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P22681	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P27448	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P30305	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P54253	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P56524	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P62258	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8TEW0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q92934	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q96B36	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99683	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99759	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q9BZL6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q5S007	Human	PMID:29541021
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P62258	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q92934	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q5HYW2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q86Z20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P04049	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P27448	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q7KZI7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q8N5S9	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:Q99759	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAH	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:6355873|PMID:31046837
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:5487519|PMID:21390248
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	UniProtKB:O60260|UniProtKB:Q9WVS6	Mouse	MGI:MGI:3611990|PMID:16096643
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	UniProtKB:P21580	Mouse	MGI:MGI:5430903|PMID:9299557
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	PR:Q61663	Mouse	PMID:9738002
Molecular Function	GO:0005515	protein binding	Ywhah	IPI	UniProtKB:Q3MUI1	Rat	PMID:17022975|RGD:2302412
Molecular Function	GO:0019904	protein domain specific binding	Ywhah	IDA		Mouse	PMID:12446771
Molecular Function	GO:0046982	protein heterodimerization activity	YWHAH	IPI	UniProtKB:P62258	Human	PMID:11953308
Molecular Function	GO:0017080	sodium channel regulator activity	YWHAH	IDA		Human	PMID:16728661
Molecular Function	GO:0044325	transmembrane transporter binding	YWHAH	IPI	UniProtKB:Q12809	Human	PMID:11953308
Molecular Function	GO:0044325	transmembrane transporter binding	YWHAH	IPI	UniProtKB:Q14524	Human	PMID:16728661
Molecular Function	GO:0044325	transmembrane transporter binding	Ywhah	IPI	UniProtKB:Q14524	Mouse	MGI:MGI:3714891|PMID:16728661
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	Ywhah	IMP		Mouse	PMID:15543142
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	Ywhah	IPI		Mouse	PMID:15543142
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	Ywhah	IDA		Mouse	PMID:15543142
Cellular Component	GO:0005737	cytoplasm	Ywhah	IDA		Mouse	PMID:9738002
Cellular Component	GO:0070062	extracellular exosome	YWHAH	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	YWHAH	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	YWHAH	HDA		Human	PMID:20458337
Cellular Component	GO:0098978	glutamatergic synapse	Ywhah	IDA		Mouse	PMID:15543142
Cellular Component	GO:0098978	glutamatergic synapse	Ywhah	IPI		Mouse	PMID:15543142
Cellular Component	GO:0005886	plasma membrane	YWHAH	IDA		Human	PMID:16728661
Cellular Component	GO:0098793	presynapse	Ywhah	IDA		Mouse	PMID:15543142
Cellular Component	GO:0098793	presynapse	Ywhah	IPI		Mouse	PMID:15543142
Cellular Component	GO:0045202	synapse	Ywhah	IDA		Rat	PMID:7964746|RGD:13702149
Biological Process	GO:0006713	glucocorticoid catabolic process	YWHAH	IDA		Human	PMID:15790729
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	YWHAH	IDA		Human	PMID:15790729
Biological Process	GO:0006886	intracellular protein transport	Ywhah	IDA		Mouse	PMID:12446771
Biological Process	GO:0086010	membrane depolarization during action potential	YWHAH	IDA		Human	PMID:16728661
Biological Process	GO:0050774	negative regulation of dendrite morphogenesis	Ywhah	IDA		Mouse	PMID:9738002
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	YWHAH	IDA		Human	PMID:15790729
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Ywhah	IPI		Mouse	PMID:15543142
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Ywhah	IDA		Mouse	PMID:15543142
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Ywhah	IMP		Mouse	PMID:15543142
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	YWHAH	IDA		Human	PMID:16728661
Biological Process	GO:0002028	regulation of sodium ion transport	YWHAH	IDA		Human	PMID:16728661
Biological Process	GO:0021762	substantia nigra development	YWHAH	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern