Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YWHAQ
  • Mouse genes Ywhaq
  • Rat genes Ywhaq
  • Zfish genes ywhaqa,ywhaqb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ywhaq

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	Ywhaq	IPI	RGD:3399	Rat	PMID:17308302|RGD:1642660
Molecular Function	GO:0042802	identical protein binding	YWHAQ	IPI	UniProtKB:P27348	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P05783	Human	PMID:10954706
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P22681	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q99698	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q99759	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P22681	Human	PMID:15094368
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P23945	Human	PMID:15196694
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q8WYL5	Human	PMID:15660133
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:B7UM99	Human	PMID:16367866
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:O94921	Human	PMID:16775625
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q9P0K1-3	Human	PMID:16868027
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P31946	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P61981	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P62258	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P56524	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q14678	Human	PMID:18458160
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q14678-2	Human	PMID:18458160
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q9UQC2	Human	PMID:19172738
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P30304	Human	PMID:19289404
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q8WYL5	Human	PMID:19371722
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q14678	Human	PMID:19559006
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q96PX8	Human	PMID:19640509
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P67828	Human	PMID:19860830
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P23945	Human	PMID:20600589
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q5S007	Human	PMID:20642453
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P62258	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P62258	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q92934	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q5S007	Human	PMID:23075850
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q8WUA7	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q9NU19	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q9UBF8	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P61588	Human	PMID:23622247
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P56524	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P31946	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q5S007	Human	PMID:24351927
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q5S007	Human	PMID:24947832
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q8IWZ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q6ZS17-2	Human	PMID:25588844
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:O15553	Human	PMID:27030597
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P30304	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q3KP66	Human	PMID:28436939
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P31946	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P56524	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P62258	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q92934	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q99759	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q8IWZ5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P62258	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q92934	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:Q86Z20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P04049	Human	PMID:7760835
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P22681	Human	PMID:8663231
Molecular Function	GO:0005515	protein binding	YWHAQ	IPI	UniProtKB:P22681	Human	PMID:9092538
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	UniProtKB:P23242	Mouse	MGI:MGI:5644009|PMID:24163432
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	UniProtKB:P11688	Mouse	MGI:MGI:5644009|PMID:24163432
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:6355873|PMID:31046837
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:5487519|PMID:21390248
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	PR:Q8K3V4	Mouse	PMID:18463355
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	PR:Q61337	Mouse	PMID:12944463
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	RGD:1312049	Rat	PMID:17457363|RGD:2307106
Molecular Function	GO:0005515	protein binding	Ywhaq	IPI	RGD:620103	Rat	PMID:22757651|RGD:10053724
Molecular Function	GO:0019904	protein domain specific binding	Ywhaq	IDA		Mouse	PMID:12446771
Molecular Function	GO:0044325	transmembrane transporter binding	Ywhaq	IPI	RGD:68398	Rat	PMID:22911758|RGD:9693692
Cellular Component	GO:0005737	cytoplasm	YWHAQ	IDA		Human	PMID:15163635
Cellular Component	GO:0070062	extracellular exosome	YWHAQ	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	YWHAQ	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	YWHAQ	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	YWHAQ	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	YWHAQ	HDA		Human	PMID:19946888
Cellular Component	GO:0032991	protein-containing complex	YWHAQ	IDA		Human	PMID:22797923
Cellular Component	GO:0032991	protein-containing complex	Ywhaq	IDA		Rat	PMID:17457363|RGD:2307106
Cellular Component	GO:0045202	synapse	Ywhaq	IDA		Rat	PMID:22911758|RGD:9693692
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	YWHAQ	IDA		Human	PMID:15163635
Biological Process	GO:0034766	negative regulation of monoatomic ion transmembrane transport	Ywhaq	IMP		Rat	PMID:22911758|RGD:9693692
Biological Process	GO:0006605	protein targeting	Ywhaq	IDA		Mouse	PMID:12446771
Biological Process	GO:0007264	small GTPase mediated signal transduction	Ywhaq	IPI	UniProtKB:O35929	Mouse	PMID:9211421
Biological Process	GO:0021762	substantia nigra development	YWHAQ	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern