Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YY1
  • Mouse genes Yy1
  • Rat genes Yy1
  • Zfish genes yy1a,yy1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Yy1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Yy1	IDA		Mouse	PMID:24137001
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	YY1	IMP		Human	PMID:15329343
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	YY1	IDA		Human	PMID:16260628
Molecular Function	GO:0003677	DNA binding	YY1	IDA		Human	PMID:21729784
Molecular Function	GO:0003677	DNA binding	Yy1	IDA		Mouse	PMID:15161869
Molecular Function	GO:0003677	DNA binding	Yy1	IDA		Mouse	PMID:12527199
Molecular Function	GO:0003677	DNA binding	Yy1	IDA		Mouse	PMID:15574595
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	YY1	IDA		Human	PMID:30241939
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Yy1	IDA		Mouse	PMID:11861914
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	YY1	IDA		Human	PMID:15329343
Molecular Function	GO:0140297	DNA-binding transcription factor binding	YY1	IPI	UniProtKB:P01106	Human	PMID:15674325
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	YY1	IDA		Human	PMID:1655281
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Yy1	IDA		Mouse	MGI:MGI:5487530|PMID:20843790
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Yy1	IDA		Mouse	MGI:MGI:5754467|PMID:24675724
Molecular Function	GO:0000400	four-way junction DNA binding	YY1	IDA		Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8CCI5	Human	PMID:10369680
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9H869	Human	PMID:14744866
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9H869-2	Human	PMID:14744866
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:O96019	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P78527	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9ULG1	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y230	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y265	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P49407	Human	PMID:19879840
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P28799	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q5VUG0	Human	PMID:23385818
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9ULG1	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:O96019	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9ULG1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y230	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y265	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9H869	Human	PMID:27939641
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y230	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y265	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P22301	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P60370	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q15428	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q2TAL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q49A12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q6L8G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8IWZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q969G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q96IK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYJ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYP8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9BYS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9H944	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9HD64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9NQ30	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9UBR4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:O15354	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P28799-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P45973	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P50454	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P54725	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:O96019	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q969G2	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9ULG1	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q9Y230	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:P03259	Human	PMID:7853498
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8JSK4	Human	PMID:7853498
Molecular Function	GO:0005515	protein binding	YY1	IPI	UniProtKB:Q8IY57	Human	PMID:9016636
Molecular Function	GO:0005515	protein binding	Yy1	IPI	UniProtKB:O70343|UniProtKB:Q8K4Q0|UniProtKB:Q9JLN9	Mouse	MGI:MGI:3767379|PMID:18046414
Molecular Function	GO:0005515	protein binding	Yy1	IPI	UniProtKB:Q8CG47	Mouse	MGI:MGI:5484711|PMID:23531880
Molecular Function	GO:0005515	protein binding	Yy1	IPI	UniProtKB:P48432	Mouse	MGI:MGI:3850573|PMID:19536159
Molecular Function	GO:0005515	protein binding	Yy1	IPI	UniProtKB:O09106,UniProtKB:Q60520,UniProtKB:Q9DB00	Mouse	MGI:MGI:5700293|PMID:21454521
Molecular Function	GO:0005515	protein binding	Yy1	IPI	PR:Q921E6	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Yy1	IPI	PR:P25916	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Yy1	IPI	RGD:3773	Rat	PMID:10713133|RGD:9588247
Molecular Function	GO:0005515	protein binding	yy1a	IPI	ZFIN:ZDB-GENE-030131-1117,ZFIN:ZDB-GENE-060824-1	Zfish	PMID:19879840
Molecular Function	GO:0003723	RNA binding	YY1	IDA		Human	PMID:21729784
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	YY1	IDA		Human	PMID:30241939
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Yy1	IDA		Mouse	PMID:17107999
Molecular Function	GO:0043565	sequence-specific DNA binding	Yy1	IDA		Mouse	PMID:23942234
Molecular Function	GO:0043565	sequence-specific DNA binding	Yy1	IDA		Rat	PMID:10713133|RGD:9588247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	YY1	IDA		Human	PMID:28473536
Molecular Function	GO:0046332	SMAD binding	YY1	IMP		Human	PMID:15329343
Molecular Function	GO:0000976	transcription cis-regulatory region binding	YY1	IDA		Human	PMID:9857059
Cellular Component	GO:0000785	chromatin	Yy1	IDA		Mouse	MGI:MGI:5754467|PMID:24675724
Cellular Component	GO:0005677	chromatin silencing complex	Yy1	IDA		Mouse	PMID:26658965
Cellular Component	GO:0005737	cytoplasm	Yy1	IDA		Rat	PMID:9215534|RGD:9588269
Cellular Component	GO:0031011	Ino80 complex	YY1	IDA		Human	PMID:21303910
Cellular Component	GO:0031011	Ino80 complex	YY1	IDA		Human	PMID:18026119
Cellular Component	GO:0016363	nuclear matrix	Yy1	IDA		Rat	PMID:9215534|RGD:9588269
Cellular Component	GO:0005634	nucleus	YY1	IDA		Human	PMID:10791971
Cellular Component	GO:0005634	nucleus	YY1	IDA		Human	PMID:16260628
Cellular Component	GO:0005634	nucleus	YY1	IDA		Human	PMID:18026119
Cellular Component	GO:0005634	nucleus	YY1	IMP		Human	PMID:22065573
Cellular Component	GO:0005634	nucleus	Yy1	IDA		Mouse	PMID:9857059
Cellular Component	GO:0005634	nucleus	Yy1	IDA		Mouse	PMID:20720167
Cellular Component	GO:0005634	nucleus	Yy1	IDA		Rat	PMID:11487577|RGD:628455
Cellular Component	GO:0031519	PcG protein complex	Yy1	IDA		Mouse	PMID:16624538
Cellular Component	GO:0031519	PcG protein complex	Yy1	IDA		Mouse	PMID:17001316
Cellular Component	GO:0005667	transcription regulator complex	Yy1	IDA		Mouse	PMID:11861914
Cellular Component	GO:0005667	transcription regulator complex	Yy1	IDA		Rat	PMID:11487577|RGD:628455
Biological Process	GO:0001525	angiogenesis	yy1a	IMP	ZFIN:ZDB-MRPHLNO-171006-4	Zfish	PMID:27913726
Biological Process	GO:0009952	anterior/posterior pattern specification	Yy1	IGI	MGI:MGI:1101770	Mouse	PMID:16624538
Biological Process	GO:0009952	anterior/posterior pattern specification	Yy1	IMP	MGI:MGI:2445451	Mouse	PMID:16624538
Biological Process	GO:0030183	B cell differentiation	Yy1	IMP	MGI:MGI:3624790	Mouse	PMID:23531880
Biological Process	GO:0007420	brain development	yy1a	IMP	ZFIN:ZDB-MRPHLNO-100311-2	Zfish	PMID:26924789
Biological Process	GO:0048593	camera-type eye morphogenesis	Yy1	IGI	MGI:MGI:1101770	Mouse	PMID:16624538
Biological Process	GO:0071347	cellular response to interleukin-1	Yy1	IDA		Rat	PMID:10860774|RGD:9588259
Biological Process	GO:0034644	cellular response to UV	YY1	IMP		Human	PMID:18026119
Biological Process	GO:0006338	chromatin remodeling	YY1	IDA		Human	PMID:21303910
Biological Process	GO:0051276	chromosome organization	Yy1	IMP		Mouse	MGI:MGI:5009388|PMID:18026119
Biological Process	GO:0006974	DNA damage response	YY1	IMP		Human	PMID:18026119
Biological Process	GO:0006974	DNA damage response	Yy1	IMP		Mouse	MGI:MGI:5009388|PMID:18026119
Biological Process	GO:0000724	double-strand break repair via homologous recombination	YY1	IMP		Human	PMID:18026119
Biological Process	GO:0010467	gene expression	Yy1	IDA		Mouse	PMID:23942234
Biological Process	GO:0007507	heart development	yy1a	IMP	ZFIN:ZDB-MRPHLNO-100311-2	Zfish	PMID:26924789
Biological Process	GO:0030097	hemopoiesis	Yy1	IMP	MGI:MGI:3624790	Mouse	PMID:23531880
Biological Process	GO:0071707	immunoglobulin heavy chain V-D-J recombination	Yy1	IMP	MGI:MGI:3624790	Mouse	PMID:23531880
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	Yy1	IMP		Rat	PMID:18632988|RGD:9588273
Biological Process	GO:0010629	negative regulation of gene expression	YY1	IMP		Human	PMID:22065573
Biological Process	GO:0032688	negative regulation of interferon-beta production	YY1	IDA		Human	PMID:16260628
Biological Process	GO:1902894	negative regulation of miRNA transcription	Yy1	IDA		Mouse	MGI:MGI:5754467|PMID:24675724
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	YY1	IDA		Human	PMID:9857059
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	YY1	IDA		Human	PMID:16260628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	YY1	IDA		Human	PMID:1655281
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	YY1	IDA		Human	PMID:1946405
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Yy1	IDA		Mouse	MGI:MGI:5487530|PMID:20843790
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Yy1	IDA		Mouse	PMID:9857059
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Yy1	IMP		Rat	PMID:24469401|RGD:9588257
Biological Process	GO:0045739	positive regulation of DNA repair	Yy1	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	YY1	IMP		Human	PMID:27641337
Biological Process	GO:0010628	positive regulation of gene expression	Yy1	IDA		Mouse	PMID:24101522
Biological Process	GO:0010628	positive regulation of gene expression	yy1a	IMP	ZFIN:ZDB-MRPHLNO-100311-2	Zfish	PMID:26924789
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	Yy1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Yy1	IMP		Rat	PMID:16539685|RGD:9588264
Biological Process	GO:0051726	regulation of cell cycle	YY1	IMP		Human	PMID:26340092
Biological Process	GO:0033044	regulation of chromosome organization	YY1	IMP		Human	PMID:26340092
Biological Process	GO:0006282	regulation of DNA repair	Yy1	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0006275	regulation of DNA replication	YY1	IMP		Human	PMID:25016522
Biological Process	GO:0060382	regulation of DNA strand elongation	YY1	IMP		Human	PMID:25016522
Biological Process	GO:0006355	regulation of DNA-templated transcription	Yy1	IDA		Mouse	PMID:11861914
Biological Process	GO:0006355	regulation of DNA-templated transcription	Yy1	IDA		Rat	PMID:11487577|RGD:628455
Biological Process	GO:0045995	regulation of embryonic development	Yy1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0046890	regulation of lipid biosynthetic process	yy1b	IGI	ZFIN:ZDB-GENO-130708-1,ZFIN:ZDB-MRPHLNO-130617-1	Zfish	PMID:23416188
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	YY1	IDA		Human	PMID:15329343
Biological Process	GO:0034696	response to prostaglandin F	Yy1	IEP		Rat	PMID:11861536|RGD:634518
Biological Process	GO:0010225	response to UV-C	YY1	IMP		Human	PMID:18026119
Biological Process	GO:0010225	response to UV-C	Yy1	IMP		Mouse	MGI:MGI:5009388|PMID:18026119
Biological Process	GO:0006403	RNA localization	Yy1	IMP		Mouse	PMID:21729784
Biological Process	GO:0007283	spermatogenesis	Yy1	IMP		Mouse	MGI:MGI:4412132|PMID:19786570
Biological Process	GO:0000723	telomere maintenance	Yy1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0070328	triglyceride homeostasis	yy1b	IGI	ZFIN:ZDB-GENO-130708-1,ZFIN:ZDB-MRPHLNO-130617-2	Zfish	PMID:23416188

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern