Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZAR1
  • Mouse genes Zar1
  • Rat genes Zar1
  • Zfish genes zar1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zar1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140693	molecular condensate scaffold activity	Zar1	IDA		Mouse	PMID:36264786
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Zar1	IDA		Mouse	PMID:36264786
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Zar1	IDA		Mouse	PMID:31598710
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-030616-590	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-050626-121	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-030131-6199	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-030131-5968	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-031124-2	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-060818-3	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IPI	ZFIN:ZDB-GENE-040727-2	Zfish	PMID:27913641
Molecular Function	GO:0003729	mRNA binding	zar1	IDA		Zfish	PMID:27913641
Molecular Function	GO:0005515	protein binding	ZAR1	IPI	UniProtKB:Q96FJ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	zar1	IPI	ZFIN:ZDB-GENE-001201-3	Zfish	PMID:27913641
Molecular Function	GO:0005515	protein binding	zar1	IPI	ZFIN:ZDB-GENE-030131-5836	Zfish	PMID:27913641
Molecular Function	GO:0005515	protein binding	zar1	IPI	ZFIN:ZDB-GENE-050320-113	Zfish	PMID:27913641
Molecular Function	GO:0005515	protein binding	zar1	IPI	ZFIN:ZDB-GENE-990927-1	Zfish	PMID:27913641
Molecular Function	GO:0140610	RNA sequestering activity	Zar1	IDA		Mouse	PMID:36264786
Molecular Function	GO:0045182	translation regulator activity	Zar1	IDA		Mouse	PMID:36264786
Molecular Function	GO:0030371	translation repressor activity	zar1	IDA		Zfish	PMID:27913641
Cellular Component	GO:0005737	cytoplasm	Zar1	IDA		Mouse	MGI:MGI:2449364|PMID:12539046
Cellular Component	GO:0005737	cytoplasm	Zar1	IDA		Mouse	PMID:20014101
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	Zar1	IDA		Mouse	MGI:MGI:6378784|PMID:31598710
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	Zar1	IDA		Mouse	PMID:36264786
Cellular Component	GO:0032991	protein-containing complex	zar1	IPI	ZFIN:ZDB-GENE-990927-1	Zfish	PMID:27913641
Cellular Component	GO:0032991	protein-containing complex	zar1	IPI	ZFIN:ZDB-GENE-030131-5836	Zfish	PMID:27913641
Cellular Component	GO:0032991	protein-containing complex	zar1	IPI	ZFIN:ZDB-GENE-001201-3	Zfish	PMID:27913641
Cellular Component	GO:0032991	protein-containing complex	zar1	IPI	ZFIN:ZDB-GENE-050320-113	Zfish	PMID:27913641
Biological Process	GO:0048255	mRNA stabilization	Zar1	IDA		Mouse	PMID:36264786
Biological Process	GO:0017148	negative regulation of translation	Zar1	IDA		Mouse	MGI:MGI:6378784|PMID:31598710
Biological Process	GO:0017148	negative regulation of translation	Zar1	IDA		Mouse	PMID:36264786
Biological Process	GO:0017148	negative regulation of translation	zar1	IDA		Zfish	PMID:27913641|ZFIN:ZDB-PUB-161204-2
Biological Process	GO:0017148	negative regulation of translation	zar1	IDA		Zfish	PMID:27913641
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	Zar1	IDA		Mouse	PMID:36264786
Biological Process	GO:0001556	oocyte maturation	Zar1	IDA		Mouse	PMID:31598710
Biological Process	GO:0001556	oocyte maturation	Zar1	IDA		Mouse	PMID:36264786
Biological Process	GO:1905881	positive regulation of oogenesis	zar1	IMP	ZFIN:ZDB-GENO-170302-4	Zfish	PMID:27913641
Biological Process	GO:0006412	translation	zar1	IMP	ZFIN:ZDB-GENO-170302-4	Zfish	PMID:27913641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern