Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Zbp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ZBP1
- Mouse genes Zbp1
- Rat genes Zbp1
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	ZBP1	IDA		Human	PMID:17618271
Molecular Function	GO:0003677	DNA binding	Zbp1	IDA		Mouse	PMID:17618271
Molecular Function	GO:0003725	double-stranded RNA binding	Zbp1	IDA		Mouse	MGI:MGI:6434626\|PMID:32296175
Molecular Function	GO:0003725	double-stranded RNA binding	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Molecular Function	GO:0003692	left-handed Z-DNA binding	Zbp1	IDA		Mouse	PMID:11524677
Molecular Function	GO:0005515	protein binding	ZBP1	IPI	UniProtKB:Q13601	Human	PMID:19590578
Molecular Function	GO:0005515	protein binding	ZBP1	IPI	UniProtKB:Q9Y572	Human	PMID:19590578
Molecular Function	GO:0005515	protein binding	ZBP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZBP1	IPI	UniProtKB:P08543	Human	PMID:33348174
Molecular Function	GO:0005515	protein binding	Zbp1	IPI	UniProtKB:Q9QZL0	Mouse	MGI:MGI:6436371\|PMID:22423968
Molecular Function	GO:0005515	protein binding	Zbp1	IPI	UniProtKB:P56545\|UniProtKB:Q13114\|UniProtKB:Q13363\|UniProtKB:Q6UX71\|UniProtKB:Q9ULE6	Mouse	MGI:MGI:5292417\|PMID:21903422
Molecular Function	GO:0005515	protein binding	Zbp1	IPI	UniProtKB:Q9QZL0	Mouse	MGI:MGI:5927398\|PMID:28607035
Cellular Component	GO:0005737	cytoplasm	ZBP1	IDA		Human	PMID:16876127
Cellular Component	GO:0005737	cytoplasm	ZBP1	IDA		Human	PMID:16990255
Cellular Component	GO:0005737	cytoplasm	ZBP1	IDA		Human	PMID:19158679
Cellular Component	GO:0005737	cytoplasm	Zbp1	IDA		Mouse	MGI:MGI:5927398\|PMID:28607035
Cellular Component	GO:0005737	cytoplasm	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Cellular Component	GO:0005737	cytoplasm	Zbp1	IDA		Mouse	MGI:MGI:6434626\|PMID:32296175
Cellular Component	GO:0005829	cytosol	ZBP1	IDA		Human	PMID:17618271
Cellular Component	GO:0005634	nucleus	ZBP1	IDA		Human	PMID:16876127
Cellular Component	GO:0005634	nucleus	ZBP1	IDA		Human	PMID:16990255
Cellular Component	GO:0005634	nucleus	ZBP1	IDA		Human	PMID:19158679
Cellular Component	GO:0005634	nucleus	Zbp1	IDA		Mouse	MGI:MGI:5927398\|PMID:28607035
Cellular Component	GO:0005634	nucleus	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Cellular Component	GO:0005634	nucleus	Zbp1	IDA		Mouse	MGI:MGI:6434626\|PMID:32296175
Biological Process	GO:0002218	activation of innate immune response	Zbp1	IDA		Mouse	MGI:MGI:6434626\|PMID:32296175
Biological Process	GO:0002218	activation of innate immune response	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Biological Process	GO:0002218	activation of innate immune response	Zbp1	IMP		Mouse	MGI:MGI:6490907\|PMID:33109609
Biological Process	GO:0002218	activation of innate immune response	Zbp1	IMP		Mouse	MGI:MGI:6453154\|PMID:32350114
Biological Process	GO:0050832	defense response to fungus	Zbp1	IMP		Mouse	MGI:MGI:6490907\|PMID:33109609
Biological Process	GO:0051607	defense response to virus	ZBP1	IMP		Human	PMID:32200799
Biological Process	GO:0051607	defense response to virus	Zbp1	IMP		Mouse	MGI:MGI:6442612\|PMID:27917412
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6436445\|PMID:27746097
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6357088\|PMID:30635240
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6095612\|PMID:29073079
Biological Process	GO:0051607	defense response to virus	Zbp1	IMP		Mouse	MGI:MGI:6394181\|PMID:31630209
Biological Process	GO:0051607	defense response to virus	Zbp1	IMP		Mouse	MGI:MGI:6434626\|PMID:32296175
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6436371\|PMID:22423968
Biological Process	GO:0051607	defense response to virus	Zbp1	IMP		Mouse	MGI:MGI:6453154\|PMID:32350114
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:6436393\|PMID:30050136
Biological Process	GO:0051607	defense response to virus	Zbp1	IDA		Mouse	MGI:MGI:5927398\|PMID:28607035
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IMP		Mouse	MGI:MGI:6490907\|PMID:33109609
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IMP		Mouse	MGI:MGI:6453154\|PMID:32350114
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IMP		Mouse	MGI:MGI:6442612\|PMID:27917412
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IDA		Mouse	MGI:MGI:5927398\|PMID:28607035
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436445\|PMID:27746097
Biological Process	GO:0050729	positive regulation of inflammatory response	Zbp1	IMP		Mouse	MGI:MGI:5907399\|PMID:27819681
Biological Process	GO:0060545	positive regulation of necroptotic process	ZBP1	IMP		Human	PMID:32200799
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IMP		Mouse	MGI:MGI:6490907\|PMID:33109609
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6095612\|PMID:29073079
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436445\|PMID:27746097
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IMP		Mouse	MGI:MGI:5907399\|PMID:27819681
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IMP		Mouse	MGI:MGI:6453154\|PMID:32350114
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436412\|PMID:32200799
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IMP		Mouse	MGI:MGI:5907398\|PMID:27819682
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436371\|PMID:22423968
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6436393\|PMID:30050136
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IMP		Mouse	MGI:MGI:6442612\|PMID:27917412
Biological Process	GO:0060545	positive regulation of necroptotic process	Zbp1	IDA		Mouse	MGI:MGI:6434626\|PMID:32296175
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	Zbp1	IMP		Mouse	PMID:17618271
Biological Process	GO:0070269	pyroptosis	Zbp1	IMP		Mouse	MGI:MGI:6442612\|PMID:27917412
Biological Process	GO:0070269	pyroptosis	Zbp1	IMP		Mouse	MGI:MGI:6490907\|PMID:33109609
Biological Process	GO:0070269	pyroptosis	Zbp1	IMP		Mouse	MGI:MGI:6453154\|PMID:32350114
Biological Process	GO:0050727	regulation of inflammatory response	Zbp1	IMP		Mouse	MGI:MGI:6394181\|PMID:31630209
Biological Process	GO:2000659	regulation of interleukin-1-mediated signaling pathway	Zbp1	IMP		Mouse	MGI:MGI:6394181\|PMID:31630209

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.