Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Zbtb16

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ZBTB16
- Mouse genes Zbtb16
- Rat genes Zbtb16
- Zfish genes zbtb16a,zbtb16b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	ZBTB16	IDA		Human	PMID:12802276
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Zbtb16	IDA		Rat	PMID:14657020\|RGD:1566502
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB16	IDA		Human	PMID:12802276
Molecular Function	GO:0003690	double-stranded DNA binding	Zbtb16	IDA		Rat	PMID:14657020\|RGD:1566502
Molecular Function	GO:0042802	identical protein binding	ZBTB16	IPI	UniProtKB:Q05516	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	ZBTB16	IPI	UniProtKB:Q05516	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	ZBTB16	IPI	UniProtKB:Q05516	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	ZBTB16	IPI	UniProtKB:Q05516	Human	PMID:9294197
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q69383	Human	PMID:10980608
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O95751	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P14373	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8NHQ1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9NP79	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P35670	Human	PMID:16676348
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P68104	Human	PMID:16828757
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O35826	Human	PMID:17118363
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q86UE4	Human	PMID:19648967
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9NYJ8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q96DY5	Human	PMID:24359566
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q12933	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9H788-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6A162	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P14373	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q08379	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q13077	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9Y2V7	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q13547	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:B2RXF5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O00746	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O43189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O95751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:O95872	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P19474	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q00444	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6NUQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8NI38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q8WY64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q96QF0-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9BUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9GZU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9H4L5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9H707	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9NP79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9NTX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q9Y2V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:Q13547	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P29590	Human	PMID:9294197
Molecular Function	GO:0005515	protein binding	ZBTB16	IPI	UniProtKB:P29590-5	Human	PMID:9294197
Molecular Function	GO:0005515	protein binding	Zbtb16	IPI	PR:Q8BN78	Mouse	PMID:10207085
Molecular Function	GO:0005515	protein binding	Zbtb16	IPI	PR:Q8BX46	Mouse	PMID:15528197
Molecular Function	GO:0005515	protein binding	Zbtb16	IPI	RGD:69334	Rat	PMID:15925207\|RGD:9479055
Molecular Function	GO:0019904	protein domain specific binding	Zbtb16	IPI	RGD:619772	Rat	PMID:19191224\|RGD:2312786
Molecular Function	GO:0042803	protein homodimerization activity	ZBTB16	IDA		Human	PMID:8622986
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB16	IDA		Human	PMID:10688654
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB16	IDA		Human	PMID:12802276
Molecular Function	GO:0001222	transcription corepressor binding	ZBTB16	IPI	UniProtKB:Q06455	Human	PMID:10688654
Molecular Function	GO:0031703	type 2 angiotensin receptor binding	Zbtb16	IPI	RGD:2072	Rat	PMID:14657020\|RGD:1566502
Cellular Component	GO:0005829	cytosol	Zbtb16	IDA		Rat	PMID:14657020\|RGD:1566502
Cellular Component	GO:0001673	male germ cell nucleus	Zbtb16	IDA		Mouse	PMID:16564520
Cellular Component	GO:0016604	nuclear body	ZBTB16	IDA		Human	PMID:19648967
Cellular Component	GO:0016604	nuclear body	ZBTB16	IDA		Human	PMID:24359566
Cellular Component	GO:0016607	nuclear speck	ZBTB16	IDA		Human	PMID:8541544
Cellular Component	GO:0005634	nucleus	ZBTB16	IDA		Human	PMID:11929873
Cellular Component	GO:0005634	nucleus	ZBTB16	IDA		Human	PMID:21547890
Cellular Component	GO:0005634	nucleus	ZBTB16	IDA		Human	PMID:24359566
Cellular Component	GO:0005634	nucleus	ZBTB16	IDA		Human	PMID:9294197
Cellular Component	GO:0005634	nucleus	Zbtb16	IDA		Mouse	PMID:15156142
Cellular Component	GO:0005634	nucleus	Zbtb16	IDA		Rat	PMID:14657020\|RGD:1566502
Cellular Component	GO:0005634	nucleus	Zbtb16	IDA		Rat	PMID:19191224\|RGD:2312786
Cellular Component	GO:0005634	nucleus	zbtb16a	IDA		Zfish	PMID:26719025
Cellular Component	GO:0005634	nucleus	zbtb16b	IDA		Zfish	PMID:26719025
Cellular Component	GO:0005886	plasma membrane	Zbtb16	IDA		Rat	PMID:14657020\|RGD:1566502
Cellular Component	GO:0016605	PML body	ZBTB16	IDA		Human	PMID:9294197
Cellular Component	GO:0032991	protein-containing complex	ZBTB16	IMP		Human	PMID:10980608
Cellular Component	GO:0017053	transcription repressor complex	ZBTB16	IDA		Human	PMID:12802276
Biological Process	GO:0009952	anterior/posterior pattern specification	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0051216	cartilage development	ZBTB16	IDA		Human	PMID:21547890
Biological Process	GO:0008283	cell population proliferation	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0007417	central nervous system development	Zbtb16	IDA		Mouse	MGI:MGI:3687421\|PMID:8541544
Biological Process	GO:0042733	embryonic digit morphogenesis	Zbtb16	IMP		Rat	PMID:19191224\|RGD:2312786
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Zbtb16	IMP		Rat	PMID:19191224\|RGD:2312786
Biological Process	GO:0030326	embryonic limb morphogenesis	Zbtb16	IMP	MGI:MGI:1856943	Mouse	MGI:MGI:61278
Biological Process	GO:0009880	embryonic pattern specification	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0035136	forelimb morphogenesis	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0030097	hemopoiesis	ZBTB16	IDA		Human	PMID:8541544
Biological Process	GO:0030097	hemopoiesis	Zbtb16	IDA		Mouse	MGI:MGI:3687421\|PMID:8541544
Biological Process	GO:0035137	hindlimb morphogenesis	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:15156143
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	Zbtb16	IMP	MGI:MGI:1856943	Mouse	PMID:15156142
Biological Process	GO:0001823	mesonephros development	Zbtb16	IDA		Mouse	MGI:MGI:3687421\|PMID:8541544
Biological Process	GO:0008285	negative regulation of cell population proliferation	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB16	IDA		Human	PMID:12802276
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB16	IDA		Human	PMID:24359566
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	Zbtb16	IDA		Mouse	MGI:MGI:3687421\|PMID:8541544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZBTB16	IDA		Human	PMID:10688654
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZBTB16	IDA		Human	PMID:12802276
Biological Process	GO:0043931	ossification involved in bone maturation	Zbtb16	IMP		Rat	PMID:27727328\|RGD:40924666
Biological Process	GO:0043065	positive regulation of apoptotic process	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0061036	positive regulation of cartilage development	ZBTB16	IDA		Human	PMID:21547890
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	ZBTB16	IMP		Human	PMID:21547890
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ZBTB16	IDA		Human	PMID:21547890
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ZBTB16	IMP		Human	PMID:21547890
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	Zbtb16	IMP		Mouse	MGI:MGI:3807724\|PMID:18660811
Biological Process	GO:0045778	positive regulation of ossification	ZBTB16	IDA		Human	PMID:21547890
Biological Process	GO:0032481	positive regulation of type I interferon production	zbtb16a	IDA		Zfish	PMID:26719025
Biological Process	GO:0032481	positive regulation of type I interferon production	zbtb16b	IDA		Zfish	PMID:26719025
Biological Process	GO:0034504	protein localization to nucleus	Zbtb16	IDA		Rat	PMID:19191224\|RGD:2312786
Biological Process	GO:0006355	regulation of DNA-templated transcription	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0050767	regulation of neurogenesis	zbtb16a	IGI	ZFIN:ZDB-MRPHLNO-100526-1,ZFIN:ZDB-MRPHLNO-100526-2,ZFIN:ZDB-MRPHLNO-100526-3	Zfish	PMID:20080956
Biological Process	GO:0001501	skeletal system development	Zbtb16	IMP	MGI:MGI:2182708	Mouse	PMID:10835630
Biological Process	GO:0001501	skeletal system development	Zbtb16	IMP	MGI:MGI:1856943	Mouse	MGI:MGI:61278
Biological Process	GO:0001501	skeletal system development	Zbtb16	IMP	MGI:MGI:1856943	Mouse	PMID:6068186

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/15/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.