Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZBTB4
  • Mouse genes Zbtb4
  • Rat genes Zbtb4
  • Zfish genes zbtb4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	zbtb4	IPI	ZFIN:ZDB-GENE-980526-332	Zfish	PMID:20978132
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB4	IDA		Human	PMID:16354688
Molecular Function	GO:0008327	methyl-CpG binding	ZBTB4	IDA		Human	PMID:16354688
Molecular Function	GO:0010428	methyl-CpNpG binding	ZBTB4	IDA		Human	PMID:20403812
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q8NAP3	Human	PMID:16354688
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:O75182	Human	PMID:18451802
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q96ST3	Human	PMID:18451802
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:O75081	Human	PMID:23251453
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q05BL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q13137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q53G59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q5VU43-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB4	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	ZBTB4	IDA		Human	PMID:16354688
Molecular Function	GO:0019901	protein kinase binding	ZBTB4	IPI	UniProtKB:Q9H2X6	Human	PMID:19448668
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZBTB4	IDA		Human	PMID:16354688
Molecular Function	GO:0043565	sequence-specific DNA binding	ZBTB4	IDA		Human	PMID:20403812
Molecular Function	GO:0043565	sequence-specific DNA binding	zbtb4	IDA		Zfish	PMID:20978132
Cellular Component	GO:0005829	cytosol	ZBTB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	ZBTB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZBTB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZBTB4	IDA		Human	PMID:16354688
Cellular Component	GO:0005634	nucleus	zbtb4	IDA		Zfish	PMID:20978132
Biological Process	GO:0009952	anterior/posterior pattern specification	zbtb4	IDA		Zfish	PMID:20978132
Biological Process	GO:0006974	DNA damage response	ZBTB4	IDA		Human	PMID:19448668
Biological Process	GO:0060030	dorsal convergence	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-3	Zfish	PMID:20978132
Biological Process	GO:0060030	dorsal convergence	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:20978132
Biological Process	GO:0009953	dorsal/ventral pattern formation	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:20978132
Biological Process	GO:0009953	dorsal/ventral pattern formation	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-3	Zfish	PMID:20978132
Biological Process	GO:0060031	mediolateral intercalation	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:20978132
Biological Process	GO:0060031	mediolateral intercalation	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-3	Zfish	PMID:20978132
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB4	IDA		Human	PMID:16354688
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZBTB4	IDA		Human	PMID:16354688
Biological Process	GO:0006355	regulation of DNA-templated transcription	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:22473868
Biological Process	GO:0010468	regulation of gene expression	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:23021546
Biological Process	GO:0010468	regulation of gene expression	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-3	Zfish	PMID:20978132
Biological Process	GO:0010468	regulation of gene expression	zbtb4	IDA		Zfish	PMID:20978132
Biological Process	GO:0010468	regulation of gene expression	zbtb4	IMP	ZFIN:ZDB-MRPHLNO-110111-2	Zfish	PMID:20978132

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern