Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZBTB7A
  • Mouse genes Zbtb7a
  • Rat genes Zbtb7a
  • Zfish genes zbtb7a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Zbtb7a	IDA		Mouse	MGI:MGI:3688346|PMID:15337766
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZBTB7A	IDA		Human	PMID:17595526
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Zbtb7a	IMP		Mouse	MGI:MGI:6161518|PMID:29813070
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Zbtb7a	IDA		Mouse	MGI:MGI:3527922|PMID:15662416
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Zbtb7a	IDA		Rat	PMID:10477728|RGD:633299
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ZBTB7A	IPI	UniProtKB:P08047	Human	PMID:12004059
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Zbtb7a	IDA		Mouse	MGI:MGI:3688346|PMID:15337766
Molecular Function	GO:0035035	histone acetyltransferase binding	Zbtb7a	IPI	UniProtKB:O09106	Mouse	MGI:MGI:3688346|PMID:15337766
Molecular Function	GO:0050681	nuclear androgen receptor binding	ZBTB7A	IDA		Human	PMID:20812024
Molecular Function	GO:0050681	nuclear androgen receptor binding	ZBTB7A	IPI	UniProtKB:P10275	Human	PMID:20812024
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q04206	Human	PMID:15917220
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q07666	Human	PMID:24514149
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q13547	Human	PMID:24514149
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q8IX15-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q12873	Human	PMID:26816381
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q13547	Human	PMID:26816381
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q8WXI9	Human	PMID:26816381
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q9HCK8	Human	PMID:26816381
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q9NRL2	Human	PMID:26816381
Molecular Function	GO:0005515	protein binding	ZBTB7A	IPI	UniProtKB:Q04207	Human	PMID:29813070
Molecular Function	GO:0005515	protein binding	Zbtb7a	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:6161518|PMID:29813070
Molecular Function	GO:0005515	protein binding	Zbtb7a	IPI	UniProtKB:O09106	Mouse	MGI:MGI:3688346|PMID:15337766
Molecular Function	GO:0005515	protein binding	Zbtb7a	IPI	UniProtKB:O09106	Mouse	MGI:MGI:5914335|PMID:26816381
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB7A	IMP		Human	PMID:26455326
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Zbtb7a	IDA		Mouse	MGI:MGI:3688346|PMID:15337766
Molecular Function	GO:0043565	sequence-specific DNA binding	Zbtb7a	IDA		Mouse	MGI:MGI:3527922|PMID:15662416
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ZBTB7A	IDA		Human	PMID:28473536
Molecular Function	GO:0046332	SMAD binding	ZBTB7A	IDA		Human	PMID:25514493
Molecular Function	GO:0046332	SMAD binding	ZBTB7A	IPI	UniProtKB:Q13485	Human	PMID:25514493
Molecular Function	GO:0001222	transcription corepressor binding	ZBTB7A	IDA		Human	PMID:20812024
Molecular Function	GO:0001222	transcription corepressor binding	ZBTB7A	IPI	UniProtKB:O75376	Human	PMID:20812024
Molecular Function	GO:0001222	transcription corepressor binding	ZBTB7A	IPI	UniProtKB:Q9Y618	Human	PMID:20812024
Cellular Component	GO:0005737	cytoplasm	ZBTB7A	IDA		Human	PMID:15917220
Cellular Component	GO:0070418	DNA-dependent protein kinase complex	Zbtb7a	IMP		Mouse	MGI:MGI:5702356|PMID:26446488
Cellular Component	GO:0005634	nucleus	ZBTB7A	IDA		Human	PMID:15917220
Cellular Component	GO:0005634	nucleus	ZBTB7A	IDA		Human	PMID:17595526
Cellular Component	GO:0005634	nucleus	ZBTB7A	IDA		Human	PMID:26455326
Cellular Component	GO:0005634	nucleus	Zbtb7a	IDA		Rat	PMID:10477728|RGD:633299
Cellular Component	GO:0035861	site of double-strand break	Zbtb7a	IDA		Mouse	MGI:MGI:5702356|PMID:26446488
Biological Process	GO:0030183	B cell differentiation	Zbtb7a	IMP		Mouse	MGI:MGI:3710692|PMID:17495164
Biological Process	GO:0006325	chromatin organization	Zbtb7a	IMP		Mouse	MGI:MGI:6161518|PMID:29813070
Biological Process	GO:0006338	chromatin remodeling	ZBTB7A	IMP		Human	PMID:26816381
Biological Process	GO:0006351	DNA-templated transcription	Zbtb7a	IMP		Mouse	MGI:MGI:6161518|PMID:29813070
Biological Process	GO:0097680	double-strand break repair via classical nonhomologous end joining	Zbtb7a	IDA		Mouse	MGI:MGI:5702356|PMID:26446488
Biological Process	GO:0043249	erythrocyte maturation	ZBTB7A	IMP		Human	PMID:26816381
Biological Process	GO:0043249	erythrocyte maturation	Zbtb7a	IMP		Mouse	MGI:MGI:5914335|PMID:26816381
Biological Process	GO:0045444	fat cell differentiation	ZBTB7A	IMP		Human	PMID:14701838
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	ZBTB7A	IMP		Human	PMID:20812024
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB7A	IDA		Human	PMID:12004059
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB7A	IMP		Human	PMID:20812024
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZBTB7A	IMP		Human	PMID:25514493
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Zbtb7a	IMP		Mouse	MGI:MGI:3688346|PMID:15337766
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Zbtb7a	IMP		Mouse	MGI:MGI:3710692|PMID:17495164
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	Zbtb7a	IMP		Mouse	MGI:MGI:3710692|PMID:17495164
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZBTB7A	IMP		Human	PMID:20812024
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb7a	IDA		Mouse	MGI:MGI:3688346|PMID:15337766
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb7a	IDA		Mouse	PMID:15662416
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ZBTB7A	IMP		Human	PMID:25514493
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ZBTB7A	IDA		Human	PMID:15917220
Biological Process	GO:0034504	protein localization to nucleus	ZBTB7A	IMP		Human	PMID:15917220
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	ZBTB7A	IDA		Human	PMID:24514149
Biological Process	GO:0042981	regulation of apoptotic process	ZBTB7A	IMP		Human	PMID:24514149
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	Zbtb7a	IMP		Mouse	MGI:MGI:6161518|PMID:29813070
Biological Process	GO:0006355	regulation of DNA-templated transcription	Zbtb7a	IDA		Rat	PMID:10477728|RGD:633299
Biological Process	GO:0006110	regulation of glycolytic process	ZBTB7A	IMP		Human	PMID:26455326
Biological Process	GO:0045670	regulation of osteoclast differentiation	Zbtb7a	IDA		Rat	PMID:10477728|RGD:633299
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ZBTB7A	IDA		Human	PMID:14701838
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ZBTB7A	IDA		Human	PMID:17595526
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ZBTB7A	IMP		Human	PMID:26455326
Biological Process	GO:2000677	regulation of transcription regulatory region DNA binding	ZBTB7A	IDA		Human	PMID:12004059

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern