Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZBTB7B
  • Mouse genes Zbtb7b
  • Rat genes Zbtb7b
  • Zfish genes zbtb7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Zbtb7b	IDA		Mouse	PMID:8702912
Molecular Function	GO:0003677	DNA binding	Zbtb7b	IDA		Mouse	PMID:7937772
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Zbtb7b	IDA		Mouse	MGI:MGI:68608|PMID:7937772
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Zbtb7b	IDA		Mouse	PMID:8702912
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	Zbtb7b	IMP		Mouse	MGI:MGI:5446998|PMID:22730529
Molecular Function	GO:0042826	histone deacetylase binding	Zbtb7b	IPI	UniProtKB:Q6NZM9|UniProtKB:Q9Z2V6	Mouse	MGI:MGI:5446998|PMID:22730529
Molecular Function	GO:0042802	identical protein binding	Zbtb7b	IDA		Mouse	PMID:8702912
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q96G21	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:O15062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:O43639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:O60504	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:P32969	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:P41182	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:P62993	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q13526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q15014	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q5JPT6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q96C24	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q96G21	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB7B	IPI	UniProtKB:Q96HL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Zbtb7b	IPI	UniProtKB:Q61029	Mouse	MGI:MGI:5437585|PMID:22726435
Molecular Function	GO:0005515	protein binding	Zbtb7b	IPI	UniProtKB:Q8CIH5	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Zbtb7b	IPI	UniProtKB:P09405|UniProtKB:P46935|UniProtKB:P62960|UniProtKB:Q8VEK3	Mouse	MGI:MGI:5912851|PMID:28784777
Molecular Function	GO:0042803	protein homodimerization activity	Zbtb7b	IPI	UniProtKB:Q64321	Mouse	MGI:MGI:5446998|PMID:22730529
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Zbtb7b	IDA		Mouse	MGI:MGI:68608|PMID:7937772
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ZBTB7B	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	ZBTB7B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Zbtb7b	IDA		Mouse	MGI:MGI:6120228|PMID:29420538
Biological Process	GO:1990845	adaptive thermogenesis	Zbtb7b	IMP		Mouse	MGI:MGI:5912851|PMID:28784777
Biological Process	GO:0007595	lactation	Zbtb7b	IMP		Mouse	MGI:MGI:6120228|PMID:29420538
Biological Process	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	Zbtb7b	IMP		Mouse	MGI:MGI:5446998|PMID:22730529
Biological Process	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	Zbtb7b	IMP		Mouse	MGI:MGI:6140589|PMID:24880459
Biological Process	GO:0010629	negative regulation of gene expression	Zbtb7b	IDA		Mouse	PMID:23034280
Biological Process	GO:0051141	negative regulation of NK T cell proliferation	Zbtb7b	IMP		Mouse	MGI:MGI:5449456|PMID:23105140
Biological Process	GO:2000320	negative regulation of T-helper 17 cell differentiation	Zbtb7b	IMP	MGI:MGI:3530739	Mouse	PMID:23034280
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb7b	IMP		Mouse	MGI:MGI:5446998|PMID:22730529
Biological Process	GO:0001865	NK T cell differentiation	Zbtb7b	IMP		Mouse	MGI:MGI:5449456|PMID:23105140
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	Zbtb7b	IMP		Mouse	MGI:MGI:5912851|PMID:28784777
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	Zbtb7b	IMP		Mouse	MGI:MGI:6140589|PMID:24880459
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Zbtb7b	IMP		Mouse	MGI:MGI:5912851|PMID:28784777
Biological Process	GO:0010628	positive regulation of gene expression	Zbtb7b	IDA		Mouse	MGI:MGI:6140589|PMID:24880459
Biological Process	GO:0010628	positive regulation of gene expression	Zbtb7b	IDA		Mouse	PMID:21357543
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	Zbtb7b	IMP		Mouse	MGI:MGI:6120228|PMID:29420538
Biological Process	GO:0032740	positive regulation of interleukin-17 production	Zbtb7b	IMP		Mouse	MGI:MGI:5449456|PMID:23105140
Biological Process	GO:2000640	positive regulation of SREBP signaling pathway	Zbtb7b	IMP		Mouse	MGI:MGI:6120228|PMID:29420538
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Zbtb7b	IDA		Mouse	PMID:7937772
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Zbtb7b	IDA		Mouse	PMID:8702912
Biological Process	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	Zbtb7b	IMP	MGI:MGI:3817628	Mouse	PMID:18776904
Biological Process	GO:0010468	regulation of gene expression	Zbtb7b	IMP	MGI:MGI:3530739	Mouse	PMID:23034280
Biological Process	GO:0045622	regulation of T-helper cell differentiation	Zbtb7b	IMP	MGI:MGI:3817628	Mouse	PMID:18776904
Biological Process	GO:0032868	response to insulin	Zbtb7b	IMP		Mouse	MGI:MGI:6120228|PMID:29420538

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern