Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZC4H2
  • Mouse genes Zc4h2
  • Rat genes Zc4h2
  • Zfish genes zc4h2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zc4h2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:O60504	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P15622-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q96C55	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9UK11	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9ULM2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:A0A0S2Z5X4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q5VTB9	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9UK11	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9ULM2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P15622-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P41219	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P51164	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q2KHN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q494U1-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q8IY22-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q96BR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q96CN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q96MY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9H9D4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZC4H2	IPI	UniProtKB:Q9ULM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Zc4h2	IPI	PR:O35690	Mouse	PMID:32094113
Molecular Function	GO:0005515	protein binding	Zc4h2	IPI	PR:Q62066	Mouse	PMID:32094113
Cellular Component	GO:0005737	cytoplasm	ZC4H2	IDA		Human	PMID:23623388
Cellular Component	GO:0043025	neuronal cell body	Zc4h2	IDA		Mouse	PMID:32094113
Cellular Component	GO:0005634	nucleus	ZC4H2	IDA		Human	PMID:23623388
Cellular Component	GO:0005634	nucleus	ZC4H2	IDA		Human	PMID:26056227
Cellular Component	GO:0005634	nucleus	zc4h2	IDA		Zfish	PMID:26056227|ZFIN:ZDB-PUB-150610-4
Cellular Component	GO:0045211	postsynaptic membrane	ZC4H2	IDA		Human	PMID:23623388
Cellular Component	GO:0032991	protein-containing complex	ZC4H2	IDA		Human	PMID:30177510
Biological Process	GO:0007399	nervous system development	ZC4H2	IDA		Human	PMID:23623388
Biological Process	GO:0007399	nervous system development	zc4h2	IMP		Zfish	PMID:23623388|ZFIN:ZDB-PUB-130603-5
Biological Process	GO:0007528	neuromuscular junction development	zc4h2	IMP		Zfish	PMID:23623388|ZFIN:ZDB-PUB-130603-5
Biological Process	GO:0048666	neuron development	zc4h2	IMP	ZFIN:ZDB-MRPHLNO-130607-4	Zfish	PMID:23623388
Biological Process	GO:0048666	neuron development	zc4h2	IMP	ZFIN:ZDB-MRPHLNO-130607-3	Zfish	PMID:23623388
Biological Process	GO:0048665	neuron fate specification	zc4h2	IMP	ZFIN:ZDB-GENO-151118-3	Zfish	PMID:26056227
Biological Process	GO:0048665	neuron fate specification	zc4h2	IMP	ZFIN:ZDB-GENO-151118-5	Zfish	PMID:26056227
Biological Process	GO:0003358	noradrenergic neuron development	Zc4h2	IMP	MGI:MGI:6455141	Mouse	PMID:32094113
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ZC4H2	IGI	UniProtKB:Q5VTB9	Human	PMID:32094113
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Zc4h2	IGI	MGI:MGI:1913993	Mouse	PMID:32094113
Biological Process	GO:0045666	positive regulation of neuron differentiation	ZC4H2	IMP		Human	PMID:26056227
Biological Process	GO:0045666	positive regulation of neuron differentiation	zc4h2	IMP		Zfish	PMID:26056227|ZFIN:ZDB-PUB-150610-4
Biological Process	GO:0006513	protein monoubiquitination	ZC4H2	IGI	UniProtKB:Q5VTB9	Human	PMID:32094113
Biological Process	GO:0006513	protein monoubiquitination	Zc4h2	IGI	MGI:MGI:1913993	Mouse	PMID:32094113
Biological Process	GO:2000677	regulation of transcription regulatory region DNA binding	ZC4H2	IGI	UniProtKB:Q5VTB9	Human	PMID:32094113
Biological Process	GO:2000677	regulation of transcription regulatory region DNA binding	Zc4h2	IGI	MGI:MGI:1913993	Mouse	PMID:32094113
Biological Process	GO:0021522	spinal cord motor neuron differentiation	zc4h2	IMP		Zfish	PMID:23623388|ZFIN:ZDB-PUB-130603-5

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern