Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFAND2B
  • Mouse genes Zfand2b
  • Rat genes Zfand2b
  • Zfish genes zfand2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfand2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	ZFAND2B	IDA		Human	PMID:26876100
Molecular Function	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	Zfand2b	IDA		Mouse	MGI:MGI:6154515|PMID:26876100
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	Zfand2b	IDA		Mouse	MGI:MGI:5563003|PMID:24160817
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q15038	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q15038	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:G3V162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:P46379	Human	PMID:26876100
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q15038	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q9H672-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZFAND2B	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Zfand2b	IPI	UniProtKB:P08069	Mouse	MGI:MGI:5780912|PMID:26692333
Molecular Function	GO:0005515	protein binding	Zfand2b	IPI	UniProtKB:Q9R1P4	Mouse	MGI:MGI:6092631|PMID:18467495
Molecular Function	GO:0005515	protein binding	Zfand2b	IPI	PR:Q01853	Mouse	PMID:24160817
Molecular Function	GO:0043130	ubiquitin binding	Zfand2b	IDA		Mouse	MGI:MGI:6092631|PMID:18467495
Cellular Component	GO:0005783	endoplasmic reticulum	Zfand2b	IDA		Mouse	MGI:MGI:6092631|PMID:18467495
Cellular Component	GO:0016020	membrane	Zfand2b	IDA		Mouse	MGI:MGI:6092631|PMID:18467495
Cellular Component	GO:0000502	proteasome complex	Zfand2b	IDA		Mouse	MGI:MGI:6092631|PMID:18467495
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ZFAND2B	IMP		Human	PMID:26692333
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Zfand2b	IMP		Mouse	MGI:MGI:5780912|PMID:26692333
Biological Process	GO:0045047	protein targeting to ER	ZFAND2B	IMP		Human	PMID:26692333
Biological Process	GO:0045047	protein targeting to ER	Zfand2b	IMP		Mouse	MGI:MGI:5780912|PMID:26692333
Biological Process	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	Zfand2b	IMP		Mouse	MGI:MGI:5780912|PMID:26692333
Biological Process	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ZFAND2B	IMP		Human	PMID:24160817

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern