Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF219
  • Mouse genes Zfp219
  • Rat genes Zfp219
  • Zfish genes znf219
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp219

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	ZNF219	IDA		Human	PMID:14621294
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	znf219	IMP		Zfish	PMID:24155663|ZFIN:ZDB-PUB-131121-14
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZNF219	IDA		Human	PMID:14621294
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZNF219	IDA		Human	PMID:19549071
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF219	IDA		Human	PMID:14621294
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:P37840	Human	PMID:19549071
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q5I0X7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q4V328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q7L5A3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q8WV44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF219	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Zfp219	IPI	UniProtKB:Q04887	Mouse	MGI:MGI:5285147|PMID:20940257
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF219	IDA		Human	PMID:14621294
Cellular Component	GO:0005654	nucleoplasm	ZNF219	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZNF219	IDA		Human	PMID:10819330
Cellular Component	GO:0005634	nucleus	ZNF219	IDA		Human	PMID:14621294
Cellular Component	GO:0005634	nucleus	Zfp219	IDA		Mouse	MGI:MGI:5285147|PMID:20940257
Biological Process	GO:0060174	limb bud formation	Zfp219	IEP		Mouse	MGI:MGI:5285147|PMID:20940257
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZNF219	IDA		Human	PMID:14621294
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZNF219	IDA		Human	PMID:14621294
Biological Process	GO:0030903	notochord development	znf219	IMP	ZFIN:ZDB-MRPHLNO-131220-3	Zfish	PMID:24155663
Biological Process	GO:0030903	notochord development	znf219	IMP	ZFIN:ZDB-MRPHLNO-131220-4	Zfish	PMID:24155663
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Zfp219	IMP		Mouse	MGI:MGI:5285147|PMID:20940257
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Zfp219	IDA		Mouse	MGI:MGI:5285147|PMID:20940257
Biological Process	GO:0006355	regulation of DNA-templated transcription	ZNF219	IMP		Human	PMID:19549071

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern