Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFP36L2
  • Mouse genes Zfp36l2
  • Rat genes Zfp36l2
  • Zfish genes zfp36l2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp36l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	ZFP36L2	IDA		Human	PMID:20506496
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	ZFP36L2	IDA		Human	PMID:25106868
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Zfp36l2	IDA		Mouse	MGI:MGI:5320815|PMID:22367205
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Zfp36l2	IDA		Mouse	MGI:MGI:5784976|PMID:22701344
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Zfp36l2	IDA		Mouse	MGI:MGI:4818820|PMID:20622884
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Zfp36l2	IDA		Mouse	MGI:MGI:5500826|PMID:23748442
Molecular Function	GO:0005515	protein binding	ZFP36L2	IPI	UniProtKB:Q9UIV1	Human	PMID:25106868
Molecular Function	GO:0003723	RNA binding	ZFP36L2	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	Zfp36l2	IDA		Mouse	MGI:MGI:5320815|PMID:22367205
Cellular Component	GO:0005737	cytoplasm	Zfp36l2	IDA		Mouse	MGI:MGI:5784967|PMID:24733888
Cellular Component	GO:0005737	cytoplasm	Zfp36l2	IDA		Mouse	PMID:11796723
Cellular Component	GO:0005634	nucleus	Zfp36l2	IDA		Mouse	MGI:MGI:5784967|PMID:24733888
Cellular Component	GO:0005634	nucleus	Zfp36l2	IDA		Mouse	MGI:MGI:5320815|PMID:22367205
Cellular Component	GO:0005634	nucleus	Zfp36l2	IDA		Mouse	PMID:11796723
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	ZFP36L2	IMP		Human	PMID:25106868
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	Zfp36l2	IDA		Mouse	MGI:MGI:5784976|PMID:22701344
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	Zfp36l2	IDA		Mouse	MGI:MGI:4818820|PMID:20622884
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Zfp36l2	IDA		Mouse	MGI:MGI:5784967|PMID:24733888
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ZFP36L2	IDA		Human	PMID:20166898
Biological Process	GO:0060216	definitive hemopoiesis	Zfp36l2	IMP		Mouse	MGI:MGI:4360416|PMID:19633199
Biological Process	GO:0070371	ERK1 and ERK2 cascade	ZFP36L2	IDA		Human	PMID:25106868
Biological Process	GO:0030097	hemopoiesis	Zfp36l2	IMP		Mouse	MGI:MGI:5500826|PMID:23748442
Biological Process	GO:0030097	hemopoiesis	Zfp36l2	IMP	MGI:MGI:4360890	Mouse	PMID:19633199
Biological Process	GO:0000165	MAPK cascade	Zfp36l2	IDA		Mouse	MGI:MGI:5784967|PMID:24733888
Biological Process	GO:0006402	mRNA catabolic process	Zfp36l2	IDA		Mouse	MGI:MGI:5320815|PMID:22367205
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Zfp36l2	IDA		Mouse	MGI:MGI:5784976|PMID:22701344
Biological Process	GO:1901991	negative regulation of mitotic cell cycle phase transition	Zfp36l2	IMP		Mouse	MGI:MGI:5779430|PMID:27102483
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Zfp36l2	IMP		Mouse	MGI:MGI:5500826|PMID:23748442
Biological Process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Zfp36l2	IDA		Mouse	PMID:15814898
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Zfp36l2	IDA		Mouse	MGI:MGI:5320815|PMID:22367205
Biological Process	GO:0045577	regulation of B cell differentiation	Zfp36l2	IMP		Mouse	MGI:MGI:5779430|PMID:27102483
Biological Process	GO:0043488	regulation of mRNA stability	ZFP36L2	IMP		Human	PMID:25106868
Biological Process	GO:0043488	regulation of mRNA stability	Zfp36l2	IDA		Mouse	MGI:MGI:4818820|PMID:20622884
Biological Process	GO:0043488	regulation of mRNA stability	Zfp36l2	IDA		Mouse	MGI:MGI:5784976|PMID:22701344
Biological Process	GO:0043488	regulation of mRNA stability	Zfp36l2	IDA		Mouse	PMID:15467755
Biological Process	GO:0009611	response to wounding	ZFP36L2	IDA		Human	PMID:27182009
Biological Process	GO:0048103	somatic stem cell division	Zfp36l2	IMP		Mouse	MGI:MGI:5500826|PMID:23748442
Biological Process	GO:0035019	somatic stem cell population maintenance	Zfp36l2	IMP		Mouse	MGI:MGI:5500826|PMID:23748442
Biological Process	GO:0033077	T cell differentiation in thymus	Zfp36l2	IMP		Mouse	MGI:MGI:4818820|PMID:20622884
Biological Process	GO:0033077	T cell differentiation in thymus	Zfp36l2	IGI	UniProtKB:P23950	Mouse	MGI:MGI:4818820|PMID:20622884

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern