Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF451
  • Mouse genes Zfp451
  • Rat genes Zfp451
  • Zfish genes znf451
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp451

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ZNF451	IPI	UniProtKB:P63279	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ZNF451	IPI	UniProtKB:P63279	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	ZNF451	IPI	UniProtKB:P63279	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ZNF451	IPI	UniProtKB:P63279	Human	PMID:31515488
Molecular Function	GO:0061665	SUMO ligase activity	ZNF451	IDA		Human	PMID:26524494
Molecular Function	GO:0003714	transcription corepressor activity	ZNF451	IMP		Human	PMID:24324267
Molecular Function	GO:0140416	transcription regulator inhibitor activity	ZNF451	IDA		Human	PMID:24324267
Cellular Component	GO:0005634	nucleus	ZNF451	IDA		Human	PMID:24324267
Biological Process	GO:0060633	negative regulation of transcription initiation by RNA polymerase II	ZNF451	IMP		Human	PMID:24324267
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ZNF451	IMP		Human	PMID:24324267
Biological Process	GO:0016925	protein sumoylation	ZNF451	IDA		Human	PMID:26524494

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern