Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF622
  • Mouse genes Zfp622
  • Rat genes Zfp622
  • Zfish genes znf622
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp622

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990275	preribosome binding	ZNF622	IDA		Human	PMID:32669547
Molecular Function	GO:0005515	protein binding	ZNF622	IPI	UniProtKB:Q99683	Human	PMID:21771788
Molecular Function	GO:0005515	protein binding	ZNF622	IPI	UniProtKB:O75367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNF622	IPI	UniProtKB:Q8N7W2-2	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	ZNF622	HDA		Human	PMID:22658674
Cellular Component	GO:0005829	cytosol	ZNF622	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ZNF622	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	ZNF622	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZNF622	IDA		Human	GO_REF:0000052
Biological Process	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	ZNF622	IDA		Human	PMID:21771788
Biological Process	GO:0043065	positive regulation of apoptotic process	ZNF622	IDA		Human	PMID:21771788
Biological Process	GO:0046330	positive regulation of JNK cascade	ZNF622	IMP		Human	PMID:21771788
Biological Process	GO:0033674	positive regulation of kinase activity	ZNF622	IDA		Human	PMID:21771788
Biological Process	GO:0043410	positive regulation of MAPK cascade	ZNF622	IDA		Human	PMID:21771788
Biological Process	GO:0042273	ribosomal large subunit biogenesis	ZNF622	IDA		Human	PMID:33711283

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern