Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF750
  • Mouse genes Zfp750
  • Rat genes Znf750
  • Zfish genes znf750
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp750

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF750	IDA		Human	PMID:22364861
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF750	IDA		Human	PMID:32042337
Molecular Function	GO:1990841	promoter-specific chromatin binding	ZNF750	IDA		Human	PMID:27907090
Molecular Function	GO:0005515	protein binding	ZNF750	IPI	UniProtKB:P56545	Human	PMID:25416956
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF750	IDA		Human	PMID:22364861
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF750	IDA		Human	PMID:32042337
Cellular Component	GO:0005634	nucleus	ZNF750	IDA		Human	PMID:22364861
Cellular Component	GO:0005634	nucleus	ZNF750	IDA		Human	PMID:32042337
Biological Process	GO:0008544	epidermis development	ZNF750	IMP		Human	PMID:22364861
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ZNF750	IMP		Human	PMID:32042337
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZNF750	IDA		Human	PMID:32042337
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZNF750	IDA		Human	PMID:22364861
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZNF750	IMP		Human	PMID:27907090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern