Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFYVE28
  • Mouse genes Zfyve28
  • Rat genes Zfyve28
  • Zfish genes zfyve28
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfyve28

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ZFYVE28	IDA		Human	PMID:19460345
Molecular Function	GO:0005515	protein binding	ZFYVE28	IPI	UniProtKB:O75382	Human	PMID:19460345
Cellular Component	GO:0005829	cytosol	ZFYVE28	IDA		Human	PMID:19460345
Cellular Component	GO:0031901	early endosome membrane	ZFYVE28	IDA		Human	PMID:19460345
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ZFYVE28	IMP		Human	PMID:19460345
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	ZFYVE28	IMP		Human	PMID:19460345

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern