Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZHX2
  • Mouse genes Zhx2
  • Rat genes Zhx2
  • Zfish genes zhx2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zhx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	ZHX2	IPI	UniProtKB:Q9Y6X8	Human	PMID:12741956
Molecular Function	GO:0005515	protein binding	ZHX2	IPI	UniProtKB:P23511	Human	PMID:12741956
Molecular Function	GO:0005515	protein binding	ZHX2	IPI	UniProtKB:Q9UKY1	Human	PMID:12741956
Molecular Function	GO:0005515	protein binding	ZHX2	IPI	UniProtKB:Q9UKY1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ZHX2	IPI	UniProtKB:Q03403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Zhx2	IPI	UniProtKB:Q8BUR4	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Zhx2	IPI	PR:P52795	Mouse	PMID:19515908
Molecular Function	GO:0005515	protein binding	Zhx2	IPI	PR:Q8C0Q2	Mouse	PMID:14659886
Molecular Function	GO:0005515	protein binding	Zhx2	IPI	PR:Q61411	Mouse	PMID:8939998
Molecular Function	GO:0046982	protein heterodimerization activity	ZHX2	IDA		Human	PMID:12741956
Molecular Function	GO:0042803	protein homodimerization activity	ZHX2	IDA		Human	PMID:12741956
Cellular Component	GO:0005829	cytosol	ZHX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZHX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZHX2	IDA		Human	PMID:17056598
Cellular Component	GO:0005634	nucleus	ZHX2	IDA		Human	PMID:12741956
Cellular Component	GO:0005634	nucleus	Zhx2	IDA		Mouse	MGI:MGI:6214404|PMID:30146259
Cellular Component	GO:0005634	nucleus	Zhx2	IDA		Mouse	MGI:MGI:3697249|PMID:17056598
Cellular Component	GO:0005634	nucleus	Zhx2	IDA		Mouse	PMID:19515908
Biological Process	GO:0006402	mRNA catabolic process	Zhx2	IDA		Mouse	PMID:1370712
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZHX2	IDA		Human	PMID:12741956
Biological Process	GO:0045665	negative regulation of neuron differentiation	Zhx2	IDA		Mouse	PMID:19515908
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZHX2	IDA		Human	PMID:12741956
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zhx2	IDA		Mouse	PMID:19515908
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zhx2	IMP		Mouse	PMID:10673330
Biological Process	GO:0030182	neuron differentiation	Zhx2	IDA		Mouse	PMID:19515908
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Zhx2	IMP		Mouse	PMID:7523852
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Zhx2	IMP		Mouse	MGI:MGI:6214404|PMID:30146259
Biological Process	GO:0035019	somatic stem cell population maintenance	Zhx2	IDA		Mouse	PMID:19515908

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern