Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZHX3
  • Mouse genes Zhx3
  • Rat genes Zhx3
  • Zfish genes zhx3a,zhx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zhx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZHX3	IDA		Human	PMID:12659632
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Zhx3	IDA		Rat	PMID:17056598|RGD:8554795
Molecular Function	GO:0005515	protein binding	ZHX3	IPI	UniProtKB:P23511	Human	PMID:12659632
Molecular Function	GO:0005515	protein binding	ZHX3	IPI	UniProtKB:Q9UKY1	Human	PMID:12659632
Molecular Function	GO:0005515	protein binding	ZHX3	IPI	UniProtKB:Q9UBE8	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ZHX3	IPI	UniProtKB:Q9UBE8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Zhx3	IPI	PR:Q8C0C0	Mouse	PMID:14659886
Molecular Function	GO:0046982	protein heterodimerization activity	ZHX3	IDA		Human	PMID:12659632
Molecular Function	GO:0042803	protein homodimerization activity	ZHX3	IDA		Human	PMID:12659632
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Zhx3	IDA		Rat	PMID:17056598|RGD:8554795
Cellular Component	GO:0005654	nucleoplasm	ZHX3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZHX3	IDA		Human	PMID:12659632
Cellular Component	GO:0005634	nucleus	Zhx3	IDA		Mouse	MGI:MGI:3697249|PMID:17056598
Cellular Component	GO:0005634	nucleus	Zhx3	IDA		Rat	PMID:17056598|RGD:8554795
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZHX3	IDA		Human	PMID:12659632
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zhx3	IDA		Rat	PMID:17056598|RGD:8554795
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ZHX3	IMP		Human	PMID:21174497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern