Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZKSCAN3,ZKSCAN4
  • Mouse genes Zkscan3
  • Rat genes Zkscan3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zkscan3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	ZKSCAN3	IDA		Human	PMID:18940803
Molecular Function	GO:0003677	DNA binding	ZKSCAN3	IDA		Human	PMID:18940803
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZKSCAN3	IDA		Human	PMID:23434374
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZKSCAN3	IDA		Human	PMID:18940803
Molecular Function	GO:0042802	identical protein binding	ZKSCAN4	IPI	UniProtKB:Q969J2	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	ZKSCAN4	IPI	UniProtKB:Q969J2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P57086	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96IT1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9BS40	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9HCM9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NP86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NX65	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9P0L1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:A0A0S2Z6X0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P10073	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q8NF99-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96IT1	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96JS3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NWS9-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9P0L1-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P17028	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P57086	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96JS3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NX65	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9Y5A6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P17028	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96IT1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NP86	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NX65	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9P0L1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P17028	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P57086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:P60900	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q86W11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q96IT1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9BS40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NP86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9NWS9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9P0L1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9UBH0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9UJX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN4	IPI	UniProtKB:Q9Y5A6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:O15151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P57086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q5VU43-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q8IYA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P41091	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P49591	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:P54652	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q0VDC6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ZKSCAN3	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZKSCAN3	IDA		Human	PMID:18940803
Molecular Function	GO:0043565	sequence-specific DNA binding	ZKSCAN3	IDA		Human	PMID:23434374
Cellular Component	GO:0005737	cytoplasm	ZKSCAN3	IDA		Human	PMID:23434374
Cellular Component	GO:0005654	nucleoplasm	ZKSCAN4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZKSCAN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZKSCAN3	IDA		Human	PMID:18940803
Cellular Component	GO:0005634	nucleus	ZKSCAN3	IDA		Human	PMID:23434374
Biological Process	GO:0007040	lysosome organization	ZKSCAN3	IMP		Human	PMID:23434374
Biological Process	GO:0010507	negative regulation of autophagy	ZKSCAN3	IMP		Human	PMID:23434374
Biological Process	GO:2000773	negative regulation of cellular senescence	ZKSCAN3	IMP		Human	PMID:23434374
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZKSCAN3	IDA		Human	PMID:23434374
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZKSCAN3	IDA		Human	PMID:18940803
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ZKSCAN3	IDA		Human	PMID:18940803

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern