Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZMIZ1
  • Mouse genes Zmiz1
  • Rat genes Zmiz1
  • Zfish genes zmiz1a,zmiz1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zmiz1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Zmiz1	IPI	UniProtKB:Q3TKT4	Mouse	MGI:MGI:5825415|PMID:26163108
Molecular Function	GO:0046332	SMAD binding	ZMIZ1	IPI	UniProtKB:P84022	Human	PMID:16777850
Molecular Function	GO:0046332	SMAD binding	ZMIZ1	IPI	UniProtKB:Q13485	Human	PMID:16777850
Molecular Function	GO:0003713	transcription coactivator activity	ZMIZ1	IDA		Human	PMID:16777850
Cellular Component	GO:0005737	cytoplasm	ZMIZ1	IDA		Human	PMID:14609956
Cellular Component	GO:0005829	cytosol	ZMIZ1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZMIZ1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZMIZ1	IDA		Human	PMID:14609956
Cellular Component	GO:0005654	nucleoplasm	ZMIZ1	IDA		Human	PMID:16777850
Cellular Component	GO:0005634	nucleus	ZMIZ1	IDA		Human	PMID:30639322
Biological Process	GO:0030521	androgen receptor signaling pathway	ZMIZ1	IDA		Human	PMID:14609956
Biological Process	GO:0048844	artery morphogenesis	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0090398	cellular senescence	Zmiz1	IDA		Mouse	PMID:15572682
Biological Process	GO:0048589	developmental growth	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0003007	heart morphogenesis	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0001701	in utero embryonic development	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	Zmiz1	IMP		Mouse	MGI:MGI:5790022|PMID:26522984
Biological Process	GO:1903508	positive regulation of nucleic acid-templated transcription	ZMIZ1	IDA		Human	PMID:14609956
Biological Process	GO:1903508	positive regulation of nucleic acid-templated transcription	ZMIZ1	IDA		Human	PMID:16777850
Biological Process	GO:0045582	positive regulation of T cell differentiation	Zmiz1	IMP		Mouse	MGI:MGI:5790022|PMID:26522984
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZMIZ1	IDA		Human	PMID:26522984
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0021852	pyramidal neuron migration to cerebral cortex	ZMIZ1	IMP		Human	PMID:30639322
Biological Process	GO:0033233	regulation of protein sumoylation	ZMIZ1	IDA		Human	PMID:14609956
Biological Process	GO:0060395	SMAD protein signal transduction	ZMIZ1	IDA		Human	PMID:16777850
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ZMIZ1	IDA		Human	PMID:16777850
Biological Process	GO:0001570	vasculogenesis	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885
Biological Process	GO:0007296	vitellogenesis	Zmiz1	IMP	MGI:MGI:3769389	Mouse	PMID:17967885

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern