Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C4BPA
  • Mouse genes Zp3r
  • Rat genes Zp3r
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zp3r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	C4BPA	IPI	UniProtKB:P20851	Human	PMID:14607961
Molecular Function	GO:0005515	protein binding	C4BPA	IPI	UniProtKB:P13050	Human	PMID:16330538
Molecular Function	GO:0005515	protein binding	C4BPA	IPI	UniProtKB:P02741:PRO_0000023526	Human	PMID:17244159
Molecular Function	GO:0005515	protein binding	Zp3r	IPI	UniProtKB:P10761	Mouse	MGI:MGI:4942258|PMID:11417900
Molecular Function	GO:0005515	protein binding	Zp3r	IPI	PR:P10761	Mouse	PMID:7604284
Molecular Function	GO:0003723	RNA binding	C4BPA	HDA		Human	PMID:22658674
Cellular Component	GO:0043159	acrosomal matrix	Zp3r	IDA		Mouse	MGI:MGI:3687793|PMID:11133656
Cellular Component	GO:0043159	acrosomal matrix	Zp3r	IDA		Mouse	PMID:11784086
Cellular Component	GO:0043159	acrosomal matrix	Zp3r	IDA		Rat	PMID:12737520|RGD:1299568
Cellular Component	GO:0001669	acrosomal vesicle	Zp3r	IDA		Mouse	PMID:9890753
Cellular Component	GO:0001669	acrosomal vesicle	Zp3r	IDA		Mouse	PMID:25605614
Cellular Component	GO:0001669	acrosomal vesicle	Zp3r	IDA		Mouse	PMID:23976951
Cellular Component	GO:0001669	acrosomal vesicle	Zp3r	EXP		Mouse	PMID:16540102
Cellular Component	GO:0001669	acrosomal vesicle	Zp3r	IDA		Mouse	PMID:21640725
Cellular Component	GO:0072562	blood microparticle	C4BPA	HDA		Human	PMID:22516433
Cellular Component	GO:0044297	cell body	Zp3r	IDA		Mouse	PMID:21880732
Cellular Component	GO:0031410	cytoplasmic vesicle	Zp3r	IDA		Mouse	PMID:31816150
Cellular Component	GO:0005615	extracellular space	C4BPA	IDA		Human	PMID:14607961
Cellular Component	GO:0005615	extracellular space	C4BPA	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	C4BPA	IDA		Human	PMID:22333221
Cellular Component	GO:0002081	outer acrosomal membrane	Zp3r	IDA		Mouse	MGI:MGI:4942258|PMID:11417900
Cellular Component	GO:0005886	plasma membrane	Zp3r	IDA		Mouse	MGI:MGI:4942258|PMID:11417900
Cellular Component	GO:0002199	zona pellucida receptor complex	Zp3r	IDA		Mouse	PMID:21880732
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp3r	IMP		Mouse	MGI:MGI:4942258|PMID:11417900
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp3r	IDA		Mouse	PMID:21880732
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp3r	IDA		Mouse	PMID:7604284
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp3r	IMP		Rat	PMID:12737520|RGD:1299568
Biological Process	GO:0045959	negative regulation of complement activation, classical pathway	C4BPA	IDA		Human	PMID:22333221
Biological Process	GO:0045732	positive regulation of protein catabolic process	C4BPA	IDA		Human	PMID:22333221
Biological Process	GO:1903027	regulation of opsonization	C4BPA	IDA		Human	PMID:22333221
Biological Process	GO:0009609	response to symbiotic bacterium	C4BPA	IDA		Human	PMID:22333221
Biological Process	GO:0007338	single fertilization	Zp3r	IDA		Mouse	PMID:9890753

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern