Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZYX
  • Mouse genes Zyx
  • Rat genes Zyx
  • Zfish genes zyx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zyx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:O95835	Human	PMID:10831611
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:P35372	Human	PMID:23840749
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:B2R9Y1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:O14910	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q96BD5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q96HC4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NV31	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:A0A0S2Z4M0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:P50552	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9UI08-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q8WWV3	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q96BD5	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NV31	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NQ75-2	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q8WWV3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q96BD5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NV31	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:P28838	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:P50552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q8WWV3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q96KM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NQ75-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9NV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZYX	IPI	UniProtKB:Q9UI08-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Zyx	IPI	PR:Q61792	Mouse	PMID:15465019
Molecular Function	GO:0003723	RNA binding	ZYX	HDA		Human	PMID:22658674
Cellular Component	GO:0015629	actin cytoskeleton	ZYX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005912	adherens junction	ZYX	IDA		Human	PMID:8940160
Cellular Component	GO:0005829	cytosol	ZYX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	ZYX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	ZYX	IDA		Human	PMID:12417594
Cellular Component	GO:0005925	focal adhesion	ZYX	IDA		Human	PMID:18297730
Cellular Component	GO:0005925	focal adhesion	ZYX	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Zyx	IDA		Mouse	PMID:24841562
Cellular Component	GO:0005634	nucleus	ZYX	IDA		Human	PMID:24036928
Cellular Component	GO:0045335	phagocytic vesicle	Zyx	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	ZYX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001725	stress fiber	ZYX	IDA		Human	PMID:18297730
Cellular Component	GO:0001725	stress fiber	ZYX	IDA		Human	PMID:24036928
Biological Process	GO:0007160	cell-matrix adhesion	Zyx	IMP		Mouse	MGI:MGI:5582864|PMID:24036928
Biological Process	GO:0071346	cellular response to type II interferon	Zyx	IDA		Mouse	PMID:19144319
Biological Process	GO:0007229	integrin-mediated signaling pathway	ZYX	IMP		Human	PMID:24036928
Biological Process	GO:0007229	integrin-mediated signaling pathway	Zyx	IMP		Mouse	MGI:MGI:5582864|PMID:24036928
Biological Process	GO:0050727	regulation of inflammatory response	Zyx	IEP		Rat	PMID:11748220|RGD:632653
Biological Process	GO:0043149	stress fiber assembly	ZYX	IMP		Human	PMID:24036928
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ZYX	IMP		Human	PMID:24036928
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Zyx	IMP		Mouse	MGI:MGI:5582864|PMID:24036928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern