Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MT-RNR2
  • Mouse genes mt-Rnr2
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set mt-Rnr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	MT-RNR2	IPI	UniProtKB:P25089	Human	PMID:15465011
Molecular Function	GO:0001664	G protein-coupled receptor binding	MT-RNR2	IPI	UniProtKB:P25090	Human	PMID:15465011
Molecular Function	GO:0042802	identical protein binding	MT-RNR2	IPI	UniProtKB:Q8IVG9	Human	PMID:12787071
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:Q07812	Human	PMID:12732850
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P17936	Human	PMID:14561895
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:O43707	Human	PMID:15619032
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:O43521-1	Human	PMID:15661735
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P70444	Human	PMID:15661737
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P26992	Human	PMID:19386761
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:Q6UWB1	Human	PMID:19386761
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:Q96N03	Human	PMID:21393573
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:Q99549	Human	PMID:23532874
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P17936	Human	PMID:26216267
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:28282805
Molecular Function	GO:0005515	protein binding	MT-RNR2	IPI	UniProtKB:P17936	Human	PMID:30184438
Molecular Function	GO:0043621	protein self-association	MT-RNR2	IDA		Human	PMID:12860203
Molecular Function	GO:0048019	receptor antagonist activity	MT-RNR2	IDA		Human	PMID:15153530
Cellular Component	GO:0005737	cytoplasm	MT-RNR2	IDA		Human	PMID:15661735
Cellular Component	GO:0005737	cytoplasm	MT-RNR2	IDA		Human	PMID:20542501
Cellular Component	GO:0005737	cytoplasm	MT-RNR2	IDA		Human	PMID:26990160
Cellular Component	GO:0005576	extracellular region	MT-RNR2	IDA		Human	PMID:11371646
Cellular Component	GO:0005615	extracellular space	MT-RNR2	IDA		Human	PMID:26990160
Cellular Component	GO:0005739	mitochondrion	MT-RNR2	IDA		Human	PMID:15567815
Cellular Component	GO:0005739	mitochondrion	MT-RNR2	IDA		Human	PMID:20542501
Cellular Component	GO:0005739	mitochondrion	MT-RNR2	IDA		Human	PMID:26990160
Cellular Component	GO:0005634	nucleus	MT-RNR2	IDA		Human	PMID:20542501
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MT-RNR2	IDA		Human	PMID:15619032
Cellular Component	GO:0036126	sperm flagellum	MT-RNR2	IDA		Human	PMID:30920769
Cellular Component	GO:0097225	sperm midpiece	MT-RNR2	IDA		Human	PMID:20542501
Cellular Component	GO:0097225	sperm midpiece	MT-RNR2	IDA		Human	PMID:30920769
Biological Process	GO:1904646	cellular response to amyloid-beta	MT-RNR2	IDA		Human	PMID:12787071
Biological Process	GO:1904646	cellular response to amyloid-beta	MT-RNR2	IDA		Human	PMID:19386761
Biological Process	GO:0030595	leukocyte chemotaxis	MT-RNR2	IDA		Human	PMID:15153530
Biological Process	GO:0007005	mitochondrion organization	MT-RNR2	IDA		Human	PMID:29432738
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	MT-RNR2	IDA		Human	PMID:27349871
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	MT-RNR2	IDA		Human	PMID:28282805
Biological Process	GO:0043066	negative regulation of apoptotic process	MT-RNR2	IDA		Human	PMID:11327724
Biological Process	GO:0043066	negative regulation of apoptotic process	MT-RNR2	IDA		Human	PMID:15661735
Biological Process	GO:0043066	negative regulation of apoptotic process	MT-RNR2	IDA		Human	PMID:15661737
Biological Process	GO:0043066	negative regulation of apoptotic process	MT-RNR2	IDA		Human	PMID:26990160
Biological Process	GO:0043066	negative regulation of apoptotic process	MT-RNR2	IDA		Human	PMID:27783653
Biological Process	GO:0050728	negative regulation of inflammatory response	MT-RNR2	IDA		Human	PMID:32923762
Biological Process	GO:0032692	negative regulation of interleukin-1 production	MT-RNR2	IDA		Human	PMID:32923762
Biological Process	GO:0032701	negative regulation of interleukin-18 production	MT-RNR2	IDA		Human	PMID:32923762
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	MT-RNR2	IDA		Human	PMID:23277413
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	MT-RNR2	IDA		Human	PMID:12787071
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	MT-RNR2	IDA		Human	PMID:19386761
Biological Process	GO:1901215	negative regulation of neuron death	MT-RNR2	IDA		Human	PMID:12860203
Biological Process	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	MT-RNR2	IDA		Human	PMID:32923762
Biological Process	GO:1902883	negative regulation of response to oxidative stress	MT-RNR2	IDA		Human	PMID:32923762
Biological Process	GO:0097435	supramolecular fiber organization	MT-RNR2	IDA		Human	PMID:31690630
Biological Process	GO:0097435	supramolecular fiber organization	MT-RNR2	IDA		Human	PMID:33106313

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern