Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SFTPA1	HGNC:10798 (HGNC) 653509 (Entrez Gene) 178630 (OMIM) SFTPA1 (Alliance of Genome Resources)	Chr10 q22.3	Chr10:79610939-79615455 (+) GRCh38	bronchopulmonary dysplasia chronic obstructive pulmonary disease interstitial lung disease lung disease newborn respiratory distress syndrome pulmonary edema pulmonary fibrosis pulmonary tuberculosis respiratory syncytial virus infectious disease	Q8IWL2 (UniProt | EBI) NM_001164646 (RefSeq)
	SFTPA2	HGNC:10799 (HGNC) 729238 (Entrez Gene) 178642 (OMIM) SFTPA2 (Alliance of Genome Resources)	Chr10 q22.3	Chr10:79555852-79560407 (-) GRCh38	interstitial lung disease 2 newborn respiratory distress syndrome	Q8IWL1 (UniProt | EBI) NM_001098668 (RefSeq)
mouse	Sftpa1	MGI:109518 (MGI) 20387 (Entrez Gene) Gene Tree Sftpa1 (Alliance of Genome Resources)	Chr14 22.36 cM	Chr14:40853745-40858330 (+) GRCm39		20387 (NCBI Gene Model) P35242 (UniProt | EBI) NM_023134 (RefSeq)
rat	Sftpa1	RGD:3665 (Rat Genome Database) 24773 (Entrez Gene) Sftpa1 (Alliance of Genome Resources)	Chr16 p14			P08427 (UniProt | EBI) NM_001270647 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.