Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DLL3	HGNC:2909 (HGNC) 10683 (Entrez Gene) 602768 (OMIM) DLL3 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:39498895-39508481 (+) GRCh38	dysostosis spondylocostal dysostosis 1	Q9NYJ7 (UniProt | EBI) NM_016941 (RefSeq)
mouse	Dll3	MGI:1096877 (MGI) 13389 (Entrez Gene) Gene Tree Dll3 (Alliance of Genome Resources)	Chr7 16.67 cM	Chr7:27992980-28001210 (-) GRCm39	spondylocostal dysostosis	13389 (NCBI Gene Model) O88516 (UniProt | EBI) NM_007866 (RefSeq)
rat	Dll3	RGD:70953 (Rat Genome Database) 114125 (Entrez Gene) Dll3 (Alliance of Genome Resources)	Chr1 q21			O88671 (UniProt | EBI) NM_053666 (RefSeq)
zebrafish	dlb	ZDB-GENE-980526-114 (Zebrafish Model Organism Database) 30141 (Entrez Gene) dlb (Alliance of Genome Resources)	Chr5			O57409 (UniProt | EBI) NM_130958 (RefSeq)
	dlc	ZDB-GENE-000125-4 (Zebrafish Model Organism Database) 30120 (Entrez Gene) dlc (Alliance of Genome Resources)	Chr15			Q9IAT6 (UniProt | EBI) NM_130944 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.