Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EARS2	HGNC:29419 (HGNC) 124454 (Entrez Gene) 612799 (OMIM) EARS2 (Alliance of Genome Resources)	Chr16 p12.2	Chr16:23520754-23557731 (-) GRCh38	combined oxidative phosphorylation deficiency 12	Q5JPH6 (UniProt | EBI) NM_001083614 (RefSeq)
mouse	Ears2	MGI:1914667 (MGI) 67417 (Entrez Gene) Gene Tree Ears2 (Alliance of Genome Resources)	Chr7 65.3 cM	Chr7:121636436-121666486 (-) GRCm39		ENSMUSG00000030871 (Ensembl Gene Model) ENSMUSP00000033159 (Ensembl) ENSMUST00000033159 (Ensembl)
rat	Ears2	RGD:1307904 (Rat Genome Database) 361641 (Entrez Gene) Ears2 (Alliance of Genome Resources)	Chr1 q36			NP_001152965 (RefSeq) NM_001159493 (RefSeq)
zebrafish	ears2	ZDB-GENE-060825-214 (Zebrafish Model Organism Database) 751732 (Entrez Gene) ears2 (Alliance of Genome Resources)	Chr1			Q0P499 (UniProt | EBI) NM_001045442 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.