Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC7A8	HGNC:11066 (HGNC) 23428 (Entrez Gene) 604235 (OMIM) SLC7A8 (Alliance of Genome Resources)	Chr14 q11.2	Chr14:23125295-23183674 (-) GRCh38		Q9UHI5 (UniProt | EBI) NM_012244 (RefSeq)
mouse	Slc7a8	MGI:1355323 (MGI) 50934 (Entrez Gene) Gene Tree Slc7a8 (Alliance of Genome Resources)	Chr14 27.91 cM	Chr14:54959672-55019343 (-) GRCm39	sensorineural hearing loss	50934 (NCBI Gene Model) Q9QXW9 (UniProt | EBI) NM_016972 (RefSeq)
rat	Slc7a8	RGD:619904 (Rat Genome Database) 84551 (Entrez Gene) Slc7a8 (Alliance of Genome Resources)	Chr15 p13			Q9WVR6 (UniProt | EBI) NM_053442 (RefSeq)
zebrafish	slc7a8a	ZDB-GENE-121120-2 (Zebrafish Model Organism Database) 100007704 (Entrez Gene) slc7a8a (Alliance of Genome Resources)	Chr7			NP_001258826 (RefSeq) NM_001271897 (RefSeq)
	slc7a8b	ZDB-GENE-030616-586 (Zebrafish Model Organism Database) 100007990 (Entrez Gene) slc7a8b (Alliance of Genome Resources)	Chr2			XP_001346314 (RefSeq) NM_001007184 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.