Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DMXL2	HGNC:2938 (HGNC) 23312 (Entrez Gene) 612186 (OMIM) DMXL2 (Alliance of Genome Resources)	Chr15 q21.2	Chr15:51447711-51622833 (-) GRCh38	autosomal dominant nonsyndromic deafness 71 developmental and epileptic encephalopathy 81	Q8TDJ6 (UniProt | EBI) NM_001378463 (RefSeq)
mouse	Dmxl2	MGI:2444630 (MGI) 235380 (Entrez Gene) Gene Tree Dmxl2 (Alliance of Genome Resources)	Chr9 29.58 cM	Chr9:54272442-54408910 (-) GRCm39		ENSMUSG00000041268 (Ensembl Gene Model) ENSMUSP00000113705 (Ensembl) ENSMUST00000118163 (Ensembl)
rat	Dmxl2	RGD:1586163 (Rat Genome Database) 315676 (Entrez Gene) Dmxl2 (Alliance of Genome Resources)	Chr8 q24			NP_001414313 (RefSeq) NM_001427384 (RefSeq)
zebrafish	dmxl2	ZDB-GENE-031007-6 (Zebrafish Model Organism Database) 378958 (Entrez Gene) dmxl2 (Alliance of Genome Resources)	Chr18			NP_001289164 (RefSeq) NM_001302235 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.