Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FUS	HGNC:4010 (HGNC) 2521 (Entrez Gene) 137070 (OMIM) FUS (Alliance of Genome Resources)	Chr16 p11.2	Chr16:31180110-31194871 (+) GRCh38	amyotrophic lateral sclerosis amyotrophic lateral sclerosis type 6 essential tremor 4 liposarcoma neurodegenerative disease	P35637 (UniProt | EBI) NM_001170937 (RefSeq)
mouse	Fus	MGI:1353633 (MGI) 233908 (Entrez Gene) Gene Tree Fus (Alliance of Genome Resources)	Chr7 69.87 cM	Chr7:127565276-127581204 (+) GRCm39	amyotrophic lateral sclerosis type 6	233908 (NCBI Gene Model) P56959 (UniProt | EBI) NM_139149 (RefSeq)
rat	Fus	RGD:1308864 (Rat Genome Database) 317385 (Entrez Gene) Fus (Alliance of Genome Resources)	Chr1 q37			NP_001012137 (RefSeq) NM_001012137 (RefSeq)
zebrafish	fus	ZDB-GENE-040426-1010 (Zebrafish Model Organism Database) 394058 (Entrez Gene) fus (Alliance of Genome Resources)	Chr3			NP_957377 (RefSeq) NM_201083 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.