Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TIAM1	HGNC:11805 (HGNC) 7074 (Entrez Gene) 600687 (OMIM) TIAM1 (Alliance of Genome Resources)	Chr21 q22.11	Chr21:31118416-31559977 (-) GRCh38	neurodevelopmental disorder with language delay and seizures	Q13009 (UniProt | EBI) NM_003253 (RefSeq)
mouse	Tiam1	MGI:103306 (MGI) 21844 (Entrez Gene) Gene Tree Tiam1 (Alliance of Genome Resources)	Chr16 51.5 cM	Chr16:89583999-89940657 (-) GRCm39		ENSMUSG00000002489 (Ensembl Gene Model) ENSMUSP00000132137 (Ensembl) ENSMUST00000163370 (Ensembl)
rat	Tiam1	RGD:1307455 (Rat Genome Database) 304109 (Entrez Gene) Tiam1 (Alliance of Genome Resources)	Chr11 q11			NP_001094028 (RefSeq) NM_001100558 (RefSeq)
zebrafish	tiam1a	ZDB-GENE-080325-1 (Zebrafish Model Organism Database) 567621 (Entrez Gene) tiam1a (Alliance of Genome Resources)	Chr10			XP_001924044 (RefSeq)
	tiam1b	ZDB-GENE-120221-1 (Zebrafish Model Organism Database) 100330358 (Entrez Gene) tiam1b (Alliance of Genome Resources)	Chr15			XP_021322166 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.