Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HPS4	HGNC:15844 (HGNC) 89781 (Entrez Gene) 606682 (OMIM) HPS4 (Alliance of Genome Resources)	Chr22 q12.1	Chr22:26443107-26483931 (-) GRCh38	Hermansky-Pudlak syndrome Hermansky-Pudlak syndrome 4 schizophrenia	Q9NQG7 (UniProt | EBI) NM_152840 (RefSeq)
mouse	Hps4	MGI:2177742 (MGI) 192232 (Entrez Gene) Gene Tree Hps4 (Alliance of Genome Resources)	Chr5 54.69 cM	Chr5:112490949-112526280 (+) GRCm39	Hermansky-Pudlak syndrome 4 platelet storage pool deficiency	ENSMUSG00000042328 (Ensembl Gene Model) ENSMUSP00000047920 (Ensembl) ENSMUST00000035279 (Ensembl)
rat	Hps4	RGD:1308070 (Rat Genome Database) 304555 (Entrez Gene) Hps4 (Alliance of Genome Resources)	Chr12			NP_001100618 (RefSeq) NM_001107148 (RefSeq)
zebrafish	hps4	ZDB-GENE-040426-1068 (Zebrafish Model Organism Database) 393296 (Entrez Gene) hps4 (Alliance of Genome Resources)	Chr8			NP_956620 (RefSeq) NM_200326 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.