Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PHOX2B	HGNC:9143 (HGNC) 8929 (Entrez Gene) 603851 (OMIM) PHOX2B (Alliance of Genome Resources)	Chr4 p13	Chr4:41744082-41748725 (-) GRCh38	colorectal cancer congenital central hypoventilation syndrome neuroblastoma	Q99453 (UniProt | EBI) NM_003924 (RefSeq)
mouse	Phox2b	MGI:1100882 (MGI) 18935 (Entrez Gene) Gene Tree Phox2b (Alliance of Genome Resources)	Chr5 35.95 cM	Chr5:67251740-67256469 (-) GRCm39	congenital central hypoventilation syndrome	18935 (NCBI Gene Model) O35690 (UniProt | EBI) NM_008888 (RefSeq)
rat	Phox2b	RGD:1560582 (Rat Genome Database) 364152 (Entrez Gene) Phox2b (Alliance of Genome Resources)	Chr14 p11			NP_001414175 (RefSeq) NM_001427246 (RefSeq)
zebrafish	phox2ba	ZDB-GENE-090313-51 (Zebrafish Model Organism Database) 795258 (Entrez Gene) phox2ba (Alliance of Genome Resources)	Chr1			NP_001139175 (RefSeq) NM_001145703 (RefSeq)
	phox2bb	ZDB-GENE-050407-3 (Zebrafish Model Organism Database) 544654 (Entrez Gene) phox2bb (Alliance of Genome Resources)	Chr14			NP_001014818 (RefSeq) NM_001014818 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.