Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VCL	HGNC:12665 (HGNC) 7414 (Entrez Gene) 193065 (OMIM) VCL (Alliance of Genome Resources)	Chr10 q22.2	Chr10:73995193-74121363 (+) GRCh38	dilated cardiomyopathy dilated cardiomyopathy 1W hypertrophic cardiomyopathy hypertrophic cardiomyopathy 15	P18206 (UniProt | EBI) NM_003373 (RefSeq)
mouse	Vcl	MGI:98927 (MGI) 22330 (Entrez Gene) Gene Tree Vcl (Alliance of Genome Resources)	Chr14 11.53 cM	Chr14:20979466-21083744 (+) GRCm39		ENSMUSG00000021823 (Ensembl Gene Model) ENSMUSP00000022369 (Ensembl) ENSMUST00000022369 (Ensembl)
rat	Vcl	RGD:1311217 (Rat Genome Database) 305679 (Entrez Gene) Vcl (Alliance of Genome Resources)	Chr15 p16			P85972 (UniProt | EBI) NM_001107248 (RefSeq)
zebrafish	vcla	ZDB-GENE-050506-61 (Zebrafish Model Organism Database) 552980 (Entrez Gene) vcla (Alliance of Genome Resources)	Chr13			NP_001122153 (RefSeq) NM_001128681 (RefSeq)
	vclb	ZDB-GENE-131017-1 (Zebrafish Model Organism Database) 100334859 (Entrez Gene) vclb (Alliance of Genome Resources)	Chr12			NP_001304681 (RefSeq) NM_001317752 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.