Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NDUFS4	HGNC:7711 (HGNC) 4724 (Entrez Gene) 602694 (OMIM) NDUFS4 (Alliance of Genome Resources)	Chr5 q11.2	Chr5:53560633-53683338 (+) GRCh38	Leigh disease nuclear type mitochondrial complex I deficiency 1	O43181 (UniProt | EBI) NM_001318051 (RefSeq)
mouse	Ndufs4	MGI:1343135 (MGI) 17993 (Entrez Gene) Gene Tree Ndufs4 (Alliance of Genome Resources)	Chr13 64.12 cM	Chr13:114424331-114524630 (-) GRCm39	Leigh disease mitochondrial complex I deficiency	17993 (NCBI Gene Model) Q9CXZ1 (UniProt | EBI) NM_010887 (RefSeq)
rat	Ndufs4	RGD:1594380 (Rat Genome Database) 499529 (Entrez Gene) Ndufs4 (Alliance of Genome Resources)	Chr2 q14			Q5XIF3 (UniProt | EBI) NM_001025146 (RefSeq)
zebrafish	ndufs4	ZDB-GENE-050522-421 (Zebrafish Model Organism Database) 573689 (Entrez Gene) ndufs4 (Alliance of Genome Resources)	Chr5			NP_001018512 (RefSeq) NM_001020676 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.