Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALDH5A1	HGNC:408 (HGNC) 7915 (Entrez Gene) 610045 (OMIM) ALDH5A1 (Alliance of Genome Resources)	Chr6 p22.3	Chr6:24494867-24537207 (+) GRCh38	succinic semialdehyde dehydrogenase deficiency	P51649 (UniProt | EBI) NM_170740 (RefSeq)
mouse	Aldh5a1	MGI:2441982 (MGI) 214579 (Entrez Gene) Gene Tree Aldh5a1 (Alliance of Genome Resources)	Chr13 10.77 cM	Chr13:25091562-25121644 (-) GRCm39	epilepsy	ENSMUSG00000035936 (Ensembl Gene Model) ENSMUSP00000040591 (Ensembl) ENSMUST00000037615 (Ensembl)
rat	Aldh5a1	RGD:621422 (Rat Genome Database) 291133 (Entrez Gene) Aldh5a1 (Alliance of Genome Resources)	Chr17 p11			P51650 (UniProt | EBI) NM_022851 (RefSeq)
zebrafish	aldh5a1	ZDB-GENE-070228-2 (Zebrafish Model Organism Database) 565235 (Entrez Gene) aldh5a1 (Alliance of Genome Resources)	Chr16			NP_001103938 (RefSeq) NM_001110468 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.