Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ECE2	HGNC:13275 (HGNC) 9718 (Entrez Gene) 610145 (OMIM) ECE2 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:184276011-184293031 (+) GRCh38		P0DPD6 (UniProt | EBI) NM_001100120 (RefSeq)
	EEF1AKMT4-ECE2	HGNC:53615 (HGNC) 110599583 (Entrez Gene) EEF1AKMT4-ECE2 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:184249672-184293031 (+) GRCh38		P0DPD8 (UniProt | EBI) NM_014693 (RefSeq)
mouse	Ece2	MGI:1101356 (MGI) 107522 (Entrez Gene) Gene Tree Ece2 (Alliance of Genome Resources)	Chr16 12.48 cM	Chr16:20448601-20464665 (+) GRCm39		107522 (NCBI Gene Model) NP_647454 (RefSeq) NM_139293 (RefSeq)
rat	Ece2	RGD:1303039 (Rat Genome Database) 408243 (Entrez Gene) Ece2 (Alliance of Genome Resources)	Chr11 q23			NP_001002815 (RefSeq) NM_001002815 (RefSeq)
zebrafish	ece2a	ZDB-GENE-070912-214 (Zebrafish Model Organism Database) 100002136 (Entrez Gene) ece2a (Alliance of Genome Resources)	Chr2			XP_001341991 (RefSeq)
	ece2b	ZDB-GENE-131120-140 (Zebrafish Model Organism Database) 793465 (Entrez Gene) ece2b (Alliance of Genome Resources)	Chr15			NP_001289168 (RefSeq) NM_001302239 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.