Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL6R	HGNC:6019 (HGNC) 3570 (Entrez Gene) 147880 (OMIM) IL6R (Alliance of Genome Resources)	Chr1 q21.3	Chr1:154405193-154469450 (+) GRCh38	Alzheimer's disease Huntington's disease hyper IgE syndrome obesity stomach cancer	P08887 (UniProt | EBI) NM_181359 (RefSeq)
mouse	Il6ra	MGI:105304 (MGI) 16194 (Entrez Gene) Gene Tree Il6ra (Alliance of Genome Resources)	Chr3 39.19 cM	Chr3:89776631-89820503 (-) GRCm39		16194 (NCBI Gene Model) P22272 (UniProt | EBI) NM_010559 (RefSeq)
rat	Il6r	RGD:2902 (Rat Genome Database) 24499 (Entrez Gene) Il6r (Alliance of Genome Resources)	Chr2 q34			P22273 (UniProt | EBI) NM_017020 (RefSeq)
zebrafish	il6r	ZDB-GENE-080107-7 (Zebrafish Model Organism Database) 100135755 (Entrez Gene) il6r (Alliance of Genome Resources)	Chr16			NP_001317187 (RefSeq) NM_001330258 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.