Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CPS1	HGNC:2323 (HGNC) 1373 (Entrez Gene) 608307 (OMIM) CPS1 (Alliance of Genome Resources)	Chr2 q34	Chr2:210477682-210679107 (+) GRCh38	carbamoyl phosphate synthetase I deficiency disease persistent fetal circulation syndrome vascular disease	P31327 (UniProt | EBI) NM_001369256 (RefSeq)
mouse	Cps1	MGI:891996 (MGI) 227231 (Entrez Gene) Gene Tree Cps1 (Alliance of Genome Resources)	Chr1 33.75 cM	Chr1:67162185-67270418 (+) GRCm39	carbamoyl phosphate synthetase I deficiency disease	ENSMUSG00000025991 (Ensembl Gene Model) ENSMUSP00000027144 (Ensembl) ENSMUST00000027144 (Ensembl)
rat	Cps1	RGD:2395 (Rat Genome Database) 497840 (Entrez Gene) Cps1 (Alliance of Genome Resources)	Chr9 q32			P07756 (UniProt | EBI) NM_017072 (RefSeq)
zebrafish	cps1	ZDB-GENE-081105-17 (Zebrafish Model Organism Database) 555623 (Entrez Gene) cps1 (Alliance of Genome Resources)	Chr9			XP_017213327 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.