Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DISC1	HGNC:2888 (HGNC) 27185 (Entrez Gene) 605210 (OMIM) DISC1 (Alliance of Genome Resources)	Chr1 q42.2	Chr1:231626790-232041272 (+) GRCh38	Asperger syndrome autistic disorder bipolar disorder chronic fatigue syndrome major depressive disorder psychotic disorder schizophrenia schizophrenia 9	Q9NRI5 (UniProt | EBI) NM_001164549 (RefSeq)
mouse	Disc1	MGI:2447658 (MGI) 244667 (Entrez Gene) Gene Tree Disc1 (Alliance of Genome Resources)	Chr8 73.26 cM	Chr8:125780934-125988597 (+) GRCm39	melancholic depression schizophrenia	ENSMUSG00000043051 (Ensembl Gene Model) ENSMUSP00000095914 (Ensembl) ENSMUST00000098311 (Ensembl)
rat	Disc1	RGD:631359 (Rat Genome Database) 307940 (Entrez Gene) Disc1 (Alliance of Genome Resources)	Chr19 q12			Q810H6 (UniProt | EBI) NM_175596 (RefSeq)
zebrafish	disc1	ZDB-GENE-090122-1 (Zebrafish Model Organism Database) 407621 (Entrez Gene) disc1 (Alliance of Genome Resources)	Chr13			NP_001135735 (RefSeq) NM_001142263 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.