Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FRMD5	HGNC:28214 (HGNC) 84978 (Entrez Gene) 616309 (OMIM) FRMD5 (Alliance of Genome Resources)	Chr15 q15.3	Chr15:43870761-44199473 (-) GRCh38	neurodevelopmental disorder with eye movement abnormalities and ataxia	Q7Z6J6 (UniProt | EBI) NM_001411124 (RefSeq)
mouse	Frmd5	MGI:2442557 (MGI) 228564 (Entrez Gene) Gene Tree Frmd5 (Alliance of Genome Resources)	Chr2 60.42 cM	Chr2:121376010-121637568 (-) GRCm39	autism spectrum disorder	ENSMUSG00000027238 (Ensembl Gene Model) ENSMUSP00000106222 (Ensembl) ENSMUST00000110592 (Ensembl)
rat	Frmd5	RGD:1561554 (Rat Genome Database) 311362 (Entrez Gene) Frmd5 (Alliance of Genome Resources)	Chr3 q35			NP_001417360 (RefSeq) NM_001430431 (RefSeq)
zebrafish	frmd5b	ZDB-GENE-060810-165 (Zebrafish Model Organism Database) 569968 (Entrez Gene) frmd5b (Alliance of Genome Resources)	Chr7			XP_698481 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.