Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GDF6	HGNC:4221 (HGNC) 392255 (Entrez Gene) 601147 (OMIM) GDF6 (Alliance of Genome Resources)	Chr8 q22.1	Chr8:96142333-96160806 (-) GRCh38	cleft lip cleft palate isolated microphthalmia 4 Klippel-Feil syndrome 1 Leber congenital amaurosis 17 multiple synostoses syndrome 4	Q6KF10 (UniProt | EBI) NM_001001557 (RefSeq)
mouse	Gdf6	MGI:95689 (MGI) 242316 (Entrez Gene) Gene Tree Gdf6 (Alliance of Genome Resources)	Chr4 4.35 cM	Chr4:9844372-9862345 (+) GRCm39		242316 (NCBI Gene Model) P43028 (UniProt | EBI) NM_013526 (RefSeq)
rat	Gdf6	RGD:620104 (Rat Genome Database) 252834 (Entrez Gene) Gdf6 (Alliance of Genome Resources)	Chr5 q13			Q6HA10 (UniProt | EBI) NM_001013038 (RefSeq)
zebrafish	gdf6a	ZDB-GENE-980526-373 (Zebrafish Model Organism Database) 566470 (Entrez Gene) gdf6a (Alliance of Genome Resources)	Chr16			P85857 (UniProt | EBI) NM_001159994 (RefSeq)
	gdf6b	ZDB-GENE-980526-442 (Zebrafish Model Organism Database) 30180 (Entrez Gene) gdf6b (Alliance of Genome Resources)	Chr19			A8E7N9 (UniProt | EBI) NM_130987 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.