Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TIE1	HGNC:11809 (HGNC) 7075 (Entrez Gene) 600222 (OMIM) TIE1 (Alliance of Genome Resources)	Chr1 p34.2	Chr1:43300982-43323108 (+) GRCh38	hereditary lymphedema	P35590 (UniProt | EBI) NM_005424 (RefSeq)
mouse	Tie1	MGI:99906 (MGI) 21846 (Entrez Gene) Gene Tree Tie1 (Alliance of Genome Resources)	Chr4 54.67 cM	Chr4:118328388-118347046 (-) GRCm39		21846 (NCBI Gene Model) Q06806 (UniProt | EBI) NM_011587 (RefSeq)
rat	Tie1	RGD:621642 (Rat Genome Database) 89806 (Entrez Gene) Tie1 (Alliance of Genome Resources)	Chr5 q36			NP_445997 (RefSeq) NM_053545 (RefSeq)
zebrafish	tie1	ZDB-GENE-990415-55 (Zebrafish Model Organism Database) 30746 (Entrez Gene) tie1 (Alliance of Genome Resources)	Chr6			O73792 (UniProt | EBI) NM_001346150 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.