Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NF2	HGNC:7773 (HGNC) 4771 (Entrez Gene) 607379 (OMIM) NF2 (Alliance of Genome Resources)	Chr22 q12.2	Chr22:29603556-29698600 (+) GRCh38	colorectal cancer familial meningioma gastrointestinal stromal tumor hepatocellular carcinoma malignant pleural mesothelioma meningioma neurilemmoma vestibular schwannomatosis	P35240 (UniProt | EBI) NM_001407053 (RefSeq)
mouse	Nf2	MGI:97307 (MGI) 18016 (Entrez Gene) Gene Tree Nf2 (Alliance of Genome Resources)	Chr11 3.0 cM	Chr11:4715845-4799536 (-) GRCm39	coloboma otitis media renal cell carcinoma vestibular schwannomatosis	ENSMUSG00000009073 (Ensembl Gene Model) ENSMUSP00000105536 (Ensembl) ENSMUST00000109910 (Ensembl)
rat	Nf2	RGD:3169 (Rat Genome Database) 25744 (Entrez Gene) Nf2 (Alliance of Genome Resources)	Chr14 q21			Q63648 (UniProt | EBI) NM_013193 (RefSeq)
zebrafish	nf2a	ZDB-GENE-080722-7 (Zebrafish Model Organism Database) 561184 (Entrez Gene) nf2a (Alliance of Genome Resources)	Chr5			NP_001122179 (RefSeq) NM_001128707 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.