Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDHX	HGNC:21350 (HGNC) 8050 (Entrez Gene) 608769 (OMIM) PDHX (Alliance of Genome Resources)	Chr11 p13	Chr11:34915829-35020591 (+) GRCh38	pyruvate decarboxylase deficiency sarcoma	O00330 (UniProt | EBI) NM_001135024 (RefSeq)
mouse	Pdhx	MGI:1351627 (MGI) 27402 (Entrez Gene) Gene Tree Pdhx (Alliance of Genome Resources)	Chr2 54.25 cM	Chr2:102851420-102903858 (-) GRCm39		ENSMUSG00000010914 (Ensembl Gene Model) ENSMUSP00000011058 (Ensembl) ENSMUST00000011058 (Ensembl)
rat	Pdhx	RGD:1566332 (Rat Genome Database) 311254 (Entrez Gene) Pdhx (Alliance of Genome Resources)	Chr3 q32			NP_001381465 (RefSeq) NM_001394536 (RefSeq)
zebrafish	pdhx	ZDB-GENE-040426-1539 (Zebrafish Model Organism Database) 393532 (Entrez Gene) pdhx (Alliance of Genome Resources)	Chr25			NP_956854 (RefSeq) NM_200560 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.