Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PBX1	HGNC:8632 (HGNC) 5087 (Entrez Gene) 176310 (OMIM) PBX1 (Alliance of Genome Resources)	Chr1 q23.3	Chr1:164555584-164899296 (+) GRCh38	congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay	P40424 (UniProt | EBI) NM_001204963 (RefSeq)
mouse	Pbx1	MGI:97495 (MGI) 18514 (Entrez Gene) Gene Tree Pbx1 (Alliance of Genome Resources)	Chr1 75.95 cM	Chr1:167946933-168259839 (-) GRCm39	congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay	ENSMUSG00000052534 (Ensembl Gene Model) ENSMUSP00000135516 (Ensembl) ENSMUST00000176540 (Ensembl)
rat	Pbx1	RGD:1308213 (Rat Genome Database) 304947 (Entrez Gene) Pbx1 (Alliance of Genome Resources)	Chr13 q24			NP_001094151 (RefSeq) NM_001100681 (RefSeq)
zebrafish	pbx1a	ZDB-GENE-000405-1 (Zebrafish Model Organism Database) 58138 (Entrez Gene) pbx1a (Alliance of Genome Resources)	Chr2			NP_571690 (RefSeq) NM_131615 (RefSeq)
	pbx1b	ZDB-GENE-070424-11 (Zebrafish Model Organism Database) 570960 (Entrez Gene) pbx1b (Alliance of Genome Resources)	Chr6			NP_001077322 (RefSeq) NM_001083853 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.