Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GUK1	HGNC:4693 (HGNC) 2987 (Entrez Gene) 139270 (OMIM) GUK1 (Alliance of Genome Resources)	Chr1 q42.13	Chr1:228139962-228148984 (+) GRCh38		Q16774 (UniProt | EBI) NM_000858 (RefSeq)
mouse	Guk1	MGI:95871 (MGI) 14923 (Entrez Gene) Gene Tree Guk1 (Alliance of Genome Resources)	Chr11 37.05 cM	Chr11:59074701-59083069 (-) GRCm39		ENSMUSG00000020444 (Ensembl Gene Model) ENSMUSP00000127566 (Ensembl) ENSMUST00000170202 (Ensembl)
rat	Guk1	RGD:1309638 (Rat Genome Database) 303179 (Entrez Gene) Guk1 (Alliance of Genome Resources)	Chr10 q22			NP_001013133 (RefSeq) NM_001013115 (RefSeq)
zebrafish	guk1a	ZDB-GENE-040625-130 (Zebrafish Model Organism Database) 415216 (Entrez Gene) guk1a (Alliance of Genome Resources)	Chr2			NP_001002126 (RefSeq) NM_001316899 (RefSeq)
	guk1b	ZDB-GENE-020916-1 (Zebrafish Model Organism Database) 393697 (Entrez Gene) guk1b (Alliance of Genome Resources)	Chr8			NP_957018 (RefSeq) NM_200724 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.