Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TDO2	HGNC:11708 (HGNC) 6999 (Entrez Gene) 191070 (OMIM) TDO2 (Alliance of Genome Resources)	Chr4 q32.1	Chr4:155854738-155920406 (+) GRCh38	familial hypertryptophanemia Gilles de la Tourette syndrome	P48775 (UniProt | EBI) NM_005651 (RefSeq)
mouse	Tdo2	MGI:1928486 (MGI) 56720 (Entrez Gene) Gene Tree Tdo2 (Alliance of Genome Resources)	Chr3 35.97 cM	Chr3:81865719-81883035 (-) GRCm39		56720 (NCBI Gene Model) P48776 (UniProt | EBI) NM_019911 (RefSeq)
rat	Tdo2	RGD:68370 (Rat Genome Database) 64206 (Entrez Gene) Tdo2 (Alliance of Genome Resources)	Chr2 q34			P21643 (UniProt | EBI) NM_022403 (RefSeq)
zebrafish	tdo2a	ZDB-GENE-030131-1187 (Zebrafish Model Organism Database) 100008541 (Entrez Gene) tdo2a (Alliance of Genome Resources)	Chr14			A7MBU6 (UniProt | EBI) NM_001102616 (RefSeq)
	tdo2b	ZDB-GENE-030131-6014 (Zebrafish Model Organism Database) 334082 (Entrez Gene) tdo2b (Alliance of Genome Resources)	Chr11			Q7SY53 (UniProt | EBI) NM_199856 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.