Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDGFRB	HGNC:8804 (HGNC) 5159 (Entrez Gene) 173410 (OMIM) PDGFRB (Alliance of Genome Resources)	Chr5 q32	Chr5:150113839-150155872 (-) GRCh38	basal ganglia calcification glioblastoma infantile myofibromatosis myeloproliferative disorder with eosinophilia myeloproliferative neoplasm renal cell carcinoma	P09619 (UniProt | EBI) NM_001355017 (RefSeq)
mouse	Pdgfrb	MGI:97531 (MGI) 18596 (Entrez Gene) Gene Tree Pdgfrb (Alliance of Genome Resources)	Chr18 34.41 cM	Chr18:61178222-61218133 (+) GRCm39	autism spectrum disorder basal ganglia calcification infantile myofibromatosis myeloproliferative neoplasm schizophrenia severe nonproliferative diabetic retinopathy	ENSMUSG00000024620 (Ensembl Gene Model) ENSMUSP00000110929 (Ensembl) ENSMUST00000115274 (Ensembl)
rat	Pdgfrb	RGD:3285 (Rat Genome Database) 24629 (Entrez Gene) Pdgfrb (Alliance of Genome Resources)	Chr18			Q05030 (UniProt | EBI) NM_031525 (RefSeq)
zebrafish	pdgfrb	ZDB-GENE-030805-2 (Zebrafish Model Organism Database) 559529 (Entrez Gene) pdgfrb (Alliance of Genome Resources)	Chr14			NP_001177862 (RefSeq) NM_001190933 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.