Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ERBB2	HGNC:3430 (HGNC) 2064 (Entrez Gene) 164870 (OMIM) ERBB2 (Alliance of Genome Resources)	Chr17 q12	Chr17:39687914-39730426 (+) GRCh38	high grade glioma lung adenocarcinoma lung cancer mammary Paget's disease ovarian cancer prostate cancer renal cell carcinoma stomach cancer urinary bladder cancer	P04626 (UniProt | EBI) NM_001382799 (RefSeq)
mouse	Erbb2	MGI:95410 (MGI) 13866 (Entrez Gene) Gene Tree Erbb2 (Alliance of Genome Resources)	Chr11 61.75 cM	Chr11:98303310-98328542 (+) GRCm39	breast cancer dilated cardiomyopathy Hirschsprung's disease	13866 (NCBI Gene Model) P70424 (UniProt | EBI) NM_001003817 (RefSeq)
rat	Erbb2	RGD:2561 (Rat Genome Database) 24337 (Entrez Gene) Erbb2 (Alliance of Genome Resources)	Chr10 q31			P06494 (UniProt | EBI) NM_017003 (RefSeq)
zebrafish	erbb2	ZDB-GENE-031118-121 (Zebrafish Model Organism Database) 386966 (Entrez Gene) erbb2 (Alliance of Genome Resources)	Chr12			NP_956413 (RefSeq) NM_200119 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.